Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.44 |
| ▸ | CDC42 | P60953 | 1/20 | 0.44 |
| ▸ | RAC1 | P63000 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16656762 | 1.00 | ALOX5 (0.51) | ALOX5KEAP1NFE2L2FFAR1L3MBTL1 | |
| SCHEMBL16656812 | 1.00 | ALOX5 (0.51) | ALOX5KEAP1NFE2L2FFAR1L3MBTL1 | |
| SCHEMBL29330579 | 0.85 | ALOX5 (0.50) | ALOX5KEAP1NFE2L2FFAR1L3MBTL1 | |
| SCHEMBL24495053 | 0.82 | L3MBTL1 (0.46) | ALOX5L3MBTL1KMT2AMEN1TSHR | |
| SCHEMBL16656809 | 0.80 | ALOX5 (0.52) | ALOX5 | |
| SCHEMBL21798487 | 0.76 | ALOX5 (0.54) | ALOX5KMT2AMEN1PTGS2PTGS1 | |
| SCHEMBL21798482 | 0.76 | ALOX5 (0.54) | ALOX5KMT2AMEN1PTGS2PTGS1 | |
| SCHEMBL18783512 | 0.75 | TAS1R3 (0.40) | ALOX5PTGS2TSHRRAB9AALDH1A1 | |
| SCHEMBL5317085 | 0.75 | HTT (0.55) | FFAR1L3MBTL1LDHAKMT2AATM | |
| SCHEMBL27590253 | 0.75 | PDE4B (0.50) | ALOX5FFAR1L3MBTL1LDHAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210009508-A1 | Automated Synthesis of Small Molecules Using Chiral, Non-Racemic Boronates | NATIONAL SCIENCE FOUNDATION | 2021-01-14 | — | — | US | disclosed |
| US-10752577-B2 | Automated synthesis of small molecules using chiral, non-racemic boronates | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2020-08-25 | — | — | US | disclosed |
| US-20190315676-A1 | AUTOMATED SYNTHESIS OF SMALL MOLECULES USING CHIRAL, NON-RACEMIC BORONATES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2019-10-17 | — | — | US | disclosed |
| US-10239824-B2 | Automated synthesis of small molecules using chiral, non-racemic boronates | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2019-03-26 | — | — | US | disclosed |
| US-20170158614-A1 | AUTOMATED SYNTHESIS OF SMALL MOLECULES USING CHIRAL, NON-RACEMIC BORONATES | NATIONAL SCIENCE FOUNDATION | 2017-06-08 | — | — | US | disclosed |
| US-9388131-B2 | Automated synthesis of small molecules using chiral, non-racemic boronates | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2016-07-12 | — | — | US | disclosed |
| US-20150329567-A1 | Automated Synthesis of Small Molecules Using Chiral, Non-Racemic Boronates | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2015-11-19 | — | — | US | disclosed |
| US-9012658-B2 | Automated synthesis of small molecules using chiral, non-racemic boronates | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2015-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150329567-A1 | Automated Synthesis of Small Molecules Using Chiral, Non-Racemic Boronates | BTD, POLL, POLR1A | ALOX5 1847/4885KEAP1 3703/4885NFE2L2 4679/4885 |
| US-10752577-B2 | Automated synthesis of small molecules using chiral, non-racemic boronates | BTD, POLL, POLR1A | ALOX5 1847/4885KEAP1 3703/4885NFE2L2 4679/4885 |
| US-20170158614-A1 | AUTOMATED SYNTHESIS OF SMALL MOLECULES USING CHIRAL, NON-RACEMIC BORONATES | BTD, POLL, POLR1A | ALOX5 1847/4885KEAP1 3703/4885NFE2L2 4679/4885 |
| US-20190315676-A1 | AUTOMATED SYNTHESIS OF SMALL MOLECULES USING CHIRAL, NON-RACEMIC BORONATES | BTD, POLL, POLR1A | ALOX5 1847/4885KEAP1 3703/4885NFE2L2 4679/4885 |
| US-10239824-B2 | Automated synthesis of small molecules using chiral, non-racemic boronates | BTD, POLL, POLR1A | ALOX5 1847/4885KEAP1 3703/4885NFE2L2 4679/4885 |
| US-20210009508-A1 | Automated Synthesis of Small Molecules Using Chiral, Non-Racemic Boronates | BTD, POLL, POLR1A | ALOX5 1847/4885KEAP1 3703/4885NFE2L2 4679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.