Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Geraniol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.91 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.91 |
| ▸ | MEN1 | O00255 | 2/20 | 0.91 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.91 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.86 |
| ▸ | MAPT | P10636 | 2/20 | 0.86 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.86 |
| ▸ | SQLE | Q14534 | 7/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ICMT | O60725 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Geraniol SCHEMBL668456 | 1.00 | KMT2A (0.91) | KMT2AALOX15MEN1CYP3A4ALDH1A1 | |
| Nerol SCHEMBL5372628 | 1.00 | KMT2A (0.91) | KMT2AALOX15MEN1CYP3A4ALDH1A1 | |
| Geraniol SCHEMBL8124286 | 1.00 | KMT2A (0.91) | KMT2AALOX15MEN1CYP3A4ALDH1A1 | |
| Solanesol SCHEMBL6317060 | 0.98 | KMT2A (0.91) | KMT2AALOX15MEN1CYP3A4ALDH1A1 | |
| Farnesol SCHEMBL11215938 | 0.98 | KMT2A (0.91) | KMT2AALOX15MEN1CYP3A4ALDH1A1 | |
| Farnesol SCHEMBL1549561 | 0.98 | KMT2A (0.91) | KMT2AALOX15MEN1CYP3A4ALDH1A1 | |
| Geraniol SCHEMBL2874022 | 0.95 | KMT2A (1.00) | KMT2AALOX15MEN1CYP3A4ALDH1A1 | |
| Geraniol SCHEMBL21173796 | 0.95 | KMT2A (1.00) | KMT2AALOX15MEN1CYP3A4ALDH1A1 | |
| Geraniol SCHEMBL8676054 | 0.95 | KMT2A (1.00) | KMT2AALOX15MEN1CYP3A4ALDH1A1 | |
| Geraniol SCHEMBL19824 | 0.95 | KMT2A (1.00) | KMT2AALOX15MEN1CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9023374-B2 | Sanitizing compositions | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2015-05-05 | — | — | US | disclosed |
| US-20120328548-A1 | SANITIZING COMPOSITIONS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2012-12-27 | — | — | US | disclosed |
| EP-2488016-A1 | SANITIZING COMPOSITIONS | Yissum Research Development Company of the Hebrew University of Jerusalem (IL) | 2012-08-22 | — | — | EP | disclosed |
| WO-2011039630-A1 | SANITIZING COMPOSITIONS | YISSUM RESEARCH DEVELOPMENT CO. OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2011-04-07 | — | — | WO | disclosed |
| US-5756109-A | ESTERIFICATION INHIBITOR FOR SKIN DISORDER | CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) | 1998-05-26 | — | — | US | disclosed |