Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Geraniol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.91 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.91 |
| ▸ | MEN1 | O00255 | 2/20 | 0.91 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.91 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.86 |
| ▸ | MAPT | P10636 | 2/20 | 0.86 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.86 |
| ▸ | SQLE | Q14534 | 7/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ICMT | O60725 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Geraniol SCHEMBL1665820 | 1.00 | KMT2A (0.91) | KMT2AALOX15MEN1CYP3A4ALDH1A1 | |
| Nerol SCHEMBL5372628 | 1.00 | KMT2A (0.91) | KMT2AALOX15MEN1CYP3A4ALDH1A1 | |
| Geraniol SCHEMBL8124286 | 1.00 | KMT2A (0.91) | KMT2AALOX15MEN1CYP3A4ALDH1A1 | |
| Solanesol SCHEMBL6317060 | 0.98 | KMT2A (0.91) | KMT2AALOX15MEN1CYP3A4ALDH1A1 | |
| Farnesol SCHEMBL11215938 | 0.98 | KMT2A (0.91) | KMT2AALOX15MEN1CYP3A4ALDH1A1 | |
| Farnesol SCHEMBL1549561 | 0.98 | KMT2A (0.91) | KMT2AALOX15MEN1CYP3A4ALDH1A1 | |
| Geraniol SCHEMBL2874022 | 0.95 | KMT2A (1.00) | KMT2AALOX15MEN1CYP3A4ALDH1A1 | |
| Geraniol SCHEMBL21173796 | 0.95 | KMT2A (1.00) | KMT2AALOX15MEN1CYP3A4ALDH1A1 | |
| Geraniol SCHEMBL8676054 | 0.95 | KMT2A (1.00) | KMT2AALOX15MEN1CYP3A4ALDH1A1 | |
| Geraniol SCHEMBL19824 | 0.95 | KMT2A (1.00) | KMT2AALOX15MEN1CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12234253-B2 | Silicone compounds with a substituted amine group and a benefit agent moiety | THE PROCTER & GAMBLE COMPANY (US) | 2025-02-25 | — | — | US | claimed |
| US-20250051370-A1 | SILICONE COMPOUNDS | PROCTER & GAMBLE (US) | 2025-02-13 | — | — | US | claimed |
| US-20220064191-A1 | SILICONE COMPOUNDS | PROCTER & GAMBLE (US) | 2022-03-03 | — | — | US | claimed |
| EP-3218425-B1 | SILICONE COMPOUNDS | PROCTER & GAMBLE (US) | 2020-05-13 | — | — | EP | claimed |
| WO-2017196762-A1 | SILICONE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2017-11-16 | — | — | WO | claimed |
| US-20170327647-A1 | SILICONE COMPOUNDS | THE PROCTER & GAMBLE COMPANY | 2017-11-16 | — | — | US | claimed |
| EP-3218425-A1 | SILICONE COMPOUNDS | The Procter and Gamble Company (US) | 2017-09-20 | — | — | EP | claimed |
| CN-105928122-A | Air purifier for increasing air humidity | 舒尔环保科技（合肥）有限公司 | 2016-09-07 | — | — | CN | claimed |
| WO-2016077513-A1 | SILICONE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2016-05-19 | — | — | WO | claimed |
| US-20160137674-A1 | SILICONE COMPOUNDS | THE PROCTER & GAMBLE COMPANY | 2016-05-19 | — | — | US | claimed |
| EP-0529804-B1 | Catalysts comprising Copper and the use thereof in the preparation of aldehydes | UNION CAMP CORP (US) | 1996-04-17 | — | — | EP | claimed |
| EP-0101578-B1 | DISPENSING FRAGRANCES | Union Camp Corporation (US) | 1986-12-30 | — | — | EP | claimed |
| US-12234253-B2 | Silicone compounds with a substituted amine group and a benefit agent moiety | THE PROCTER & GAMBLE COMPANY (US) | 2025-02-25 | — | — | US | disclosed |
| US-20250051370-A1 | SILICONE COMPOUNDS | PROCTER & GAMBLE (US) | 2025-02-13 | — | — | US | disclosed |
| US-20240102060-A1 | ENZYMES AND METHODS FOR FERMENTATIVE PRODUCTION OF MONOTERPENE ESTERS | ISOBIONICS B.V. (NL) | 2024-03-28 | — | — | US | disclosed |
| CN-108136386-B | Method for preparing ruthenium/iron/carbon carrier catalyst | 巴斯夫欧洲公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-1219194-A | Delivery system comprising a release barrier loaded zeolite | PROCTER & GAMBLE (US) | 1999-06-09 | — | — | CN | disclosed |
| US-5756109-A | ESTERIFICATION INHIBITOR FOR SKIN DISORDER | CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) | 1998-05-26 | — | — | US | disclosed |
| US-5139562-A | Exposure to cineole, fenchone, menthol | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1992-08-18 | — | — | US | disclosed |
| WO-1992010934-A1 | INHIBITION OF POTATO SPROUTING USING VOLATILE MONOTERPENES | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, UNITED STATES DEPARTMENT OF COMMERCE (US) | 1992-07-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160137674-A1 | SILICONE COMPOUNDS | SMCHD1, SRI, SMS | KMT2A 1800/4885ALOX15 2271/4885MEN1 49/4885 |
| US-20250051370-A1 | SILICONE COMPOUNDS | SMCHD1, SRI, SMS | KMT2A 1800/4885ALOX15 2271/4885MEN1 49/4885 |
| US-12234253-B2 | Silicone compounds with a substituted amine group and a benefit agent moiety | SMS, SRM, AAAS | KMT2A 396/4885ALOX15 2826/4885MEN1 31/4885 |
| US-20220064191-A1 | SILICONE COMPOUNDS | SMCHD1, SRI, SMS | KMT2A 1800/4885ALOX15 2271/4885MEN1 49/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.