Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Farnesol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.91 |
| ▸ | MAPT | P10636 | 2/20 | 0.91 |
| ▸ | MEN1 | O00255 | 2/20 | 0.91 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.91 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.91 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.91 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.91 |
| ▸ | SQLE | Q14534 | 7/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ICMT | O60725 | 1/20 | 0.53 |
| ▸ | FNTA | P49354 | 1/20 | 0.50 |
| ▸ | FNTB | P49356 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Farnesol SCHEMBL1549561 | 1.00 | KMT2A (0.91) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| Solanesol SCHEMBL6317060 | 1.00 | KMT2A (0.91) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| Nerol SCHEMBL5372628 | 0.98 | KMT2A (0.91) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| Geraniol SCHEMBL1665820 | 0.98 | KMT2A (0.91) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| Geraniol SCHEMBL8124286 | 0.98 | KMT2A (0.91) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| Geraniol SCHEMBL668456 | 0.98 | KMT2A (0.91) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| Geranylgeraniol SCHEMBL23814969 | 0.95 | KMT2A (1.00) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| Farnesol SCHEMBL7546574 | 0.95 | KMT2A (1.00) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL4717874 | 0.95 | KMT2A (1.00) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL7944378 | 0.95 | KMT2A (1.00) | KMT2AMAPTMEN1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4331655-A | Cosmetic compositions and processes containing ether and acyl derivatives of 3,7,11-trimethyl-2,6,10-dodecatriene-1-ol | UNI-CHEMIE AG (CH) | 1982-05-25 | — | — | US | disclosed |