SCHEMBL1665843

SCHEMBL1665843

CCNC(=O)COC(=O)c1c(I)c(NC(C)=O)c(I)c(NC(C)=O)c1I

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.46
RAB9A P51151 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
KDM4E B2RXH2 4/20 0.41
PKM P14618 1/20 0.41
MAPK1 P28482 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.37
CYP1A2 P05177 1/20 0.36
KMT2A Q03164 1/20 0.35
HTT P42858 1/20 0.35
ALDH1A1 P00352 4/20 0.35
HPGD P15428 1/20 0.35
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9016334 0.83 LMNA (0.53) LMNARAB9AKDM4ESMN1; SMN2KMT2A
SCHEMBL6361849 0.82 LMNA (0.51) LMNARAB9AKDM4ESMN1; SMN2CYP1A2
SCHEMBL333132 0.82 LMNA (0.45) LMNAL3MBTL1KDM4ESMN1; SMN2CYP1A2
SCHEMBL332859 0.82 LMNA (0.54) LMNAKDM4EMAPK1SMN1; SMN2KMT2A
Ethyl Cartrizoate SCHEMBL2110540 0.81 LMNA (0.47) LMNAKDM4ESMN1; SMN2KMT2AALDH1A1
SCHEMBL370072 0.81 LMNA (0.50) LMNAL3MBTL1KDM4EMAPK1SMN1; SMN2
SCHEMBL9016363 0.80 LMNA (0.46) LMNAKDM4EMAPK1SMN1; SMN2CYP1A2
SCHEMBL9413528 0.79 LMNA (0.45) LMNARAB9AL3MBTL1KDM4ESMN1; SMN2
SCHEMBL8814469 0.79 LMNA (0.50) LMNAKDM4EMAPK1SMN1; SMN2KMT2A
SCHEMBL8752047 0.78 LMNA (0.44) LMNAKDM4ESMN1; SMN2KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0601616-A1 Iodinated aroyloxy carboxamides and contrast agents containing them NanoSystems L.L.C. (US) 1994-06-15 EP claimed
EP-2334393-A2 METHODS OF PROCESSING MULTI-PHASIC DISPERSIONS Baxter International Inc. (US) 2011-06-22 EP disclosed
EP-2334396-A1 METHODS OF PROCESSING MICROPARTICLES Baxter International Inc. (US) 2011-06-22 EP disclosed
EP-2334394-A1 METHODS OF PROCESSING COMPOSITIONS CONTAINING MICROPARTICLES Baxter International Inc. (US) 2011-06-22 EP disclosed
EP-2317982-A2 METHODS OF PROCESSING COMPOSITIONS CONTAINING MICROPARTICLES Baxter International Inc. (US) 2011-05-11 EP disclosed
WO-2010022276-A9 METHODS OF PROCESSING MULTI-PHASIC DISPERSIONS BAXTER INTERNATIONAL INC. (US) 2011-04-07 WO disclosed
WO-2010022282-A1 METHODS OF PROCESSING MICROPARTICLES BAXTER INTERNATIONAL INC. (US) 2010-02-25 WO disclosed
WO-2010022276-A2 METHODS OF PROCESSING MULTI-PHASIC DISPERSIONS BAXTER INTERNATIONAL INC. (US) 2010-02-25 WO disclosed
WO-2010022293-A2 METHODS OF PROCESSING COMPOSITIONS CONTAINING MICROPARTICLES BAXTER INTERNATIONAL INC. (US) 2010-02-25 WO disclosed
WO-2010022261-A1 METHODS OF PROCESSING COMPOSITIONS CONTAINING MICROPARTICLES BAXTER INTERNATIONAL INC. (US) 2010-02-25 WO disclosed
EP-0601616-A1 Iodinated aroyloxy carboxamides and contrast agents containing them NanoSystems L.L.C. (US) 1994-06-15 EP disclosed
US-5260478-A Contrast agents in x-ray imaging compositions; medical diagnosis STERLING WINTHROP INC. (US) 1993-11-09 US disclosed