Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PTPRB | P23467 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6361849 | 0.89 | LMNA (0.51) | LMNASMN1; SMN2ALDH1A1TSHRHPGD | |
| SCHEMBL370072 | 0.87 | LMNA (0.50) | LMNASMN1; SMN2ALDH1A1TSHRHPGD | |
| SCHEMBL332859 | 0.85 | LMNA (0.54) | LMNASMN1; SMN2ALDH1A1TSHRHPGD | |
| Ethyl Cartrizoate SCHEMBL2110540 | 0.84 | LMNA (0.47) | LMNASMN1; SMN2ALDH1A1TSHRTP53 | |
| SCHEMBL8230945 | 0.83 | LMNA (0.53) | LMNASMN1; SMN2ALDH1A1TSHRHPGD | |
| SCHEMBL9016363 | 0.83 | LMNA (0.46) | LMNASMN1; SMN2ALDH1A1TSHRHPGD | |
| SCHEMBL1665843 | 0.83 | LMNA (0.46) | LMNASMN1; SMN2ALDH1A1TSHRHPGD | |
| SCHEMBL9413528 | 0.82 | LMNA (0.45) | LMNASMN1; SMN2ALDH1A1TSHRHPGD | |
| SCHEMBL333132 | 0.82 | LMNA (0.45) | LMNASMN1; SMN2ALDH1A1HPGDKMT2A | |
| SCHEMBL9413518 | 0.82 | LMNA (0.45) | LMNASMN1; SMN2ALDH1A1TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749414-A1 | IODINATED AROYLOXY KETONES | NanoSystems L.L.C. (US) | 1996-12-27 | — | — | EP | claimed |
| US-5488133-A | X-RAY CONTRAST AGENTS | EASTMAN KODAK COMPANY (US) | 1996-01-30 | — | — | US | claimed |
| WO-1995024378-A1 | IODINATED AROYLOXY KETONES | NANOSYSTEMS, L.L.C. (US) | 1995-09-14 | — | — | WO | claimed |
| EP-0749414-A1 | IODINATED AROYLOXY KETONES | NanoSystems L.L.C. (US) | 1996-12-27 | — | — | EP | disclosed |
| US-5488133-A | X-RAY CONTRAST AGENTS | EASTMAN KODAK COMPANY (US) | 1996-01-30 | — | — | US | disclosed |
| WO-1995024378-A1 | IODINATED AROYLOXY KETONES | NANOSYSTEMS, L.L.C. (US) | 1995-09-14 | — | — | WO | disclosed |