Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.54 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.54 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.54 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.54 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.54 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.54 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.54 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.54 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.54 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.54 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.54 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.54 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.54 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.54 |
| ▸ | PSMB3 | P49720 | 1/20 | 0.54 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.54 |
| ▸ | PSMA6 | P60900 | 1/20 | 0.54 |
| ▸ | PSMA8 | Q8TAA3 | 1/20 | 0.54 |
| ▸ | PSMB7 | Q99436 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16658739 | 1.00 | PSMB11 (0.54) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL16658734 | 1.00 | PSMB11 (0.54) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL16658735 | 1.00 | PSMB11 (0.54) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL16658736 | 1.00 | PSMB11 (0.54) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL10016300 | 1.00 | PSMB11 (0.54) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL16658738 | 1.00 | PSMB11 (0.54) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL16658737 | 1.00 | PSMB11 (0.54) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL12048773 | 0.94 | PSMB11 (0.53) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL29498993 | 0.92 | PSMB11 (0.45) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL9806254 | 0.92 | CHRNB2 (0.47) | PSMB11PSMA7PSMB1PSMA1PSMA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2852581-B1 | NOVEL 1,3-BENZOXAZOL-2(3H)-ONES AND THEIR USE AS MEDICAMENTS AND COSMETICS | WOLFF AUGUST GMBH & CO KG ARZNEIMITTEL DR (DE) | 2016-05-04 | — | — | EP | disclosed |
| US-9199948-B2 | 1,3-benzoxazol-2(3H)-ones and their use as medicaments and cosmetics | DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) | 2015-12-01 | — | — | US | disclosed |
| US-9199948-B2 | 1,3-benzoxazol-2(3H)-ones and their use as medicaments and cosmetics | DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) | 2015-12-01 | — | — | US | disclosed |
| US-20150111935-A1 | NOVEL 1,3-BENZOXAZOL-2(3H)-ONES AND THEIR USE AS MEDICAMENTS AND COSMETICS | DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) | 2015-04-23 | — | — | US | disclosed |
| US-20150111935-A1 | NOVEL 1,3-BENZOXAZOL-2(3H)-ONES AND THEIR USE AS MEDICAMENTS AND COSMETICS | DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) | 2015-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150111935-A1 | NOVEL 1,3-BENZOXAZOL-2(3H)-ONES AND THEIR USE AS MEDICAMENTS AND COSMETICS | TRPV1, TRPA1, P2RX3 | PSMB11 2528/4885PSMA7 1966/4885PSMB1 2100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.