SCHEMBL16660304

SCHEMBL16660304

N#Cc1ccc(C(=O)Oc2ccc3ccccc3c2-c2c(OC(=O)c3ccc(O)cc3)ccc3ccccc23)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP3 P08254 2/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
CA2 P00918 2/20 0.40
CA1 P00915 1/20 0.40
SLC22A12 Q96S37 2/20 0.40
CA12 O43570 1/20 0.40
CA3 P07451 1/20 0.40
CA6 P23280 1/20 0.40
CA9 Q16790 1/20 0.40
CA14 Q9ULX7 1/20 0.40
P4HB P07237 1/20 0.39
APLNR P35414 1/20 0.39
ALDH1A1 P00352 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
HIF1A Q16665 1/20 0.38
MAPT P10636 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16660337 0.93 KMT2A (0.42) MMP3MEN1KMT2ANPC1RAB9A
SCHEMBL4943531 0.89 MAPT (0.46) MEN1KMT2AMAPTJAK2USP2
SCHEMBL17433030 0.85 KMT2A (0.49) MEN1KMT2AALDH1A1CYP1A2MAPT
SCHEMBL17432932 0.85 KMT2A (0.49) MEN1KMT2AALDH1A1CYP1A2MAPT
SCHEMBL17432991 0.85 SENP1 (0.49) MEN1KMT2ARAB9AALDH1A1MAPT
SCHEMBL16749179 0.85 KMT2A (0.39) MMP3MEN1KMT2ANPC1RAB9A
SCHEMBL17432988 0.82 MAPT (0.46) MEN1KMT2ARAB9ACYP1A2MAPT
SCHEMBL16660305 0.81 KMT2A (0.55) MEN1KMT2ANPC1CA12CA9
SCHEMBL16660338 0.80 KMT2A (0.49) MEN1KMT2ANPC1RAB9AALDH1A1
SCHEMBL16660340 0.80 KMT2A (0.54) MEN1KMT2ANPC1CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9505980-B2 Polymerizable liquid crystal composition and optically anisotropic substance having twist alignment JNC CORPORATION (JP) 2016-11-29 US disclosed
US-9399736-B2 Optically anisotropic substance and liquid crystal display JNC CORPORATION (JP) 2016-07-26 US disclosed
US-20160011349-A1 INFRARED REFLECTING FILM AND LAMINATED FILM JNC PETROCHEMICAL CORPORATION (JP) 2016-01-14 US disclosed
US-20150146156-A1 OPTICALLY ANISOTROPIC SUBSTANCE AND LIQUID CRYSTAL DISPLAY JNC CORPORATION (JP) 2015-05-28 US disclosed
US-20150108401-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION AND OPTICALLY ANISOTROPIC SUBSTANCE HAVING TWIST ALIGNMENT JNC CORPORATION (JP) 2015-04-23 US disclosed