Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 7/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20428495 | 0.88 | CASP3 (0.44) | CASP3SENP8SENP7SENP6DGAT1 | |
| SCHEMBL16660907 | 0.79 | DGAT1 (0.60) | DGAT1 | |
| SCHEMBL16787743 | 0.78 | DGAT1 (0.72) | DGAT1 | |
| SCHEMBL16787744 | 0.73 | DGAT1 (0.66) | CASP3SENP8SENP7SENP6DGAT1 | |
| SCHEMBL16787679 | 0.72 | DGAT1 (0.60) | DGAT1 | |
| SCHEMBL16787681 | 0.71 | DGAT1 (0.60) | DGAT1 | |
| SCHEMBL10558967 | 0.71 | PRMT5 (0.50) | — | |
| SCHEMBL18552826 | 0.69 | KDM4E (0.48) | CASP3SENP8SENP7SENP6DGAT1 | |
| SCHEMBL9680190 | 0.67 | CASP3 (0.73) | CASP3SENP8SENP7SENP6MAPT | |
| SCHEMBL10556612 | 0.67 | KDM4E (0.46) | MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2862856-A1 | AROMATIC HETEROCYCLIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2015-04-22 | — | — | EP | disclosed |