Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STIM1 | Q13586 | 1/20 | 0.34 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.33 |
| ▸ | RORC | P51449 | 3/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | RORB | Q92753 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2096065 | 0.77 | CES2 (0.44) | STIM1ORAI1CES2CES1ITGA4 | |
| SCHEMBL20428863 | 0.73 | STIM1 (0.36) | STIM1ORAI1CES2CES1ITGA4 | |
| SCHEMBL716995 | 0.70 | CES2 (0.48) | STIM1ORAI1CES2CES1RORC | |
| SCHEMBL30313345 | 0.70 | CES2 (0.48) | STIM1ORAI1CES2CES1RORC | |
| SCHEMBL14534757 | 0.70 | CES2 (0.39) | STIM1ORAI1CES2CES1ITGA4 | |
| SCHEMBL4710152 | 0.70 | CES2 (0.44) | STIM1ORAI1CES2CES1ITGA4 | |
| SCHEMBL5358162 | 0.68 | PTPN1 (0.48) | CTSSCNR2 | |
| SCHEMBL7939207 | 0.68 | RORC (0.42) | STIM1ORAI1CES2CES1ITGA4 | |
| SCHEMBL503596 | 0.68 | CES2 (0.50) | STIM1ORAI1CES2CES1ITGA4 | |
| SCHEMBL20560651 | 0.67 | CES2 (0.39) | STIM1ORAI1CES2CES1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2862856-A1 | AROMATIC HETEROCYCLIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2015-04-22 | — | — | EP | disclosed |