SCHEMBL3988311

SCHEMBL3988311

Nc1ccc2c(c1)C(=O)NS2(=O)=O

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA12 O43570 13/20 0.73
▸ CA9 Q16790 13/20 0.73
▸ CHEK1 O14757 1/20 0.62
▸ DAPK3 O43293 1/20 0.62
▸ MAP4K4 O95819 1/20 0.62
▸ RET P07949 1/20 0.62
▸ PIM1 P11309 1/20 0.62
▸ LTK P29376 1/20 0.62
▸ GRK5 P34947 1/20 0.62
▸ CSNK1A1 P48729 1/20 0.62
▸ CDK8 P49336 1/20 0.62
▸ PRKX P51817 1/20 0.62
▸ LIMK1 P53667 1/20 0.62
▸ CDK5 Q00535 1/20 0.62
▸ ACVR1 Q04771 1/20 0.62
▸ PTK2 Q05397 1/20 0.62
▸ TYRO3 Q06418 1/20 0.62
▸ PRKAA1 Q13131 1/20 0.62
▸ DYRK1A Q13627 1/20 0.62
▸ NTRK3 Q16288 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30873095 1.00 CA12 (0.73) CA12CA9CHEK1DAPK3MAP4K4
SCHEMBL1290860 0.85 CA12 (1.00) CA12CA9CHEK1DAPK3MAP4K4
SCHEMBL30872992 0.85 CA12 (1.00) CA12CA9CHEK1DAPK3MAP4K4
SCHEMBL29441946 0.77 CHEK1 (0.62) CA12CA9CHEK1DAPK3MAP4K4
SCHEMBL3984666 0.77 RET (1.00) CA12CA9CHEK1DAPK3MAP4K4
SCHEMBL30016818 0.77 CHEK1 (0.62) CA12CA9CHEK1DAPK3MAP4K4
SCHEMBL32689426 0.77 CHEK1 (0.62) CA12CA9CHEK1DAPK3MAP4K4
SCHEMBL2208975 0.77 CHEK1 (0.62) CA12CA9CHEK1DAPK3MAP4K4
SCHEMBL1684375 0.77 CHEK1 (0.62) CA12CA9CHEK1DAPK3MAP4K4
SCHEMBL1666180 0.77 CHEK1 (0.62) CA12CA9CHEK1DAPK3MAP4K4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260114475-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME MARS, INCORPORATED (US) 2026-04-30 — — US disclosed
EP-4702015-A1 CDK2 INHIBITORS AND METHODS OF USING SAME Shenzhen Ionova Life Science Co., Ltd. (CN) 2026-03-04 — — EP disclosed
CN-120081832-A Novel sodium channel regulator 南京清普生物科技有限公司 2025-06-03 — — CN disclosed
WO-2024222678-A1 CDK2 INHIBITORS AND METHODS OF USING SAME SHENZHEN IONOVA LIFE SCIENCE CO., LTD. (CN) 2024-10-31 — — WO disclosed
WO-2024073025-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME MARS, INCORPORATED (US) 2024-04-04 — — WO disclosed
EP-4344552-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY, AND METHODS FOR PREPARING THE SAME MARS, INCORPORATED (US) 2024-04-03 — — EP disclosed
EP-4323066-A1 MEK INHIBITORS AND USES THEREOF Ikena Oncology, Inc. (US) 2024-02-21 — — EP disclosed
CN-117580835-A MEK inhibitors and uses thereof 医肯纳肿瘤学公司 2024-02-20 — — CN disclosed
WO-2022221866-A1 MEK INHIBITORS AND USES THEREOF Ikena Oncology, Inc. (US) 2022-10-20 — — WO disclosed
WO-2022213975-A1 COMPOUNDS TARGETING Y220C MUTANT OF P53 JACOBIO PHARMACEUTICALS CO., LTD. (CN) 2022-10-13 — — WO disclosed
EP-0471756-A4 SACCHARIN DERIVATIVES USEFUL AS PROTEOLYTIC ENZYME INHIBITORS AND PREPARATION THEREOF — 1992-04-08 — — EP disclosed
EP-0471756-A1 SACCHARIN DERIVATIVES USEFUL AS PROTEOLYTIC ENZYME INHIBITORS AND PREPARATION THEREOF. STERLING WINTHROP INC (US) 1992-02-26 — — EP disclosed
EP-0235449-B1 HERBICIDAL SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-09-11 — — EP disclosed
US-4981509-A Plant growth regulators E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-01-01 — — US disclosed
WO-1990013549-A1 SACCHARIN DERIVATIVES USEFUL AS PROTEOLYTIC ENZYME INHIBITORS AND PREPARATION THEREOF STERLING WINTHROP INC. (US) 1990-11-15 — — WO disclosed
US-4871847-A Herbicidal sulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-10-03 — — US disclosed
US-4849010-A Herbicidal sulfonamides E. I. DUPONT DE NEMOURS AND COMPANY (US) 1989-07-18 — — US disclosed
US-4724039-A RICE CROP E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-02-09 — — US disclosed
US-4710221-A Herbicidal sulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-12-01 — — US disclosed
EP-0235449-A1 Herbicidal sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-09-09 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260114475-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME PIGS, TAS2R13, CEL CA12 2472/4885CA9 1611/4885CHEK1 3251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback