Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | FNTA | P49354 | 6/20 | 0.53 |
| ▸ | FNTB | P49356 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.50 |
| ▸ | SQLE | Q14534 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27740873 | 1.00 | ALDH1A1 (0.56) | ALDH1A1ALOX15KMT2AFNTAFNTB | |
| SCHEMBL29748905 | 0.98 | ALDH1A1 (0.58) | ALDH1A1ALOX15KMT2AFNTAFNTB | |
| SCHEMBL31166045 | 0.95 | ALDH1A1 (0.51) | ALDH1A1ALOX15KMT2AFNTAFNTB | |
| SCHEMBL31166044 | 0.95 | ALDH1A1 (0.51) | ALDH1A1ALOX15KMT2AFNTAFNTB | |
| SCHEMBL4461666 | 0.87 | ALDH1A1 (0.58) | ALDH1A1ALOX15KMT2AFNTAFNTB | |
| SCHEMBL3419441 | 0.87 | ALDH1A1 (0.50) | ALDH1A1ALOX15KMT2AFNTAFNTB | |
| SCHEMBL17681470 | 0.87 | ALDH1A1 (0.50) | ALDH1A1ALOX15KMT2AFNTAFNTB | |
| Squalene SCHEMBL9405154 | 0.81 | KMT2A (0.77) | ALDH1A1ALOX15KMT2AFNTAFNTB | |
| Squalene SCHEMBL9405151 | 0.81 | KMT2A (0.77) | ALDH1A1ALOX15KMT2AFNTAFNTB | |
| SCHEMBL2459793 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160257983-A1 | N-GLYCOSYLATION OF PEPTIDES AND PROTEINS | ISIS INNOVATION LIMITED (GB) | 2016-09-08 | — | — | US | disclosed |
| WO-2015056011-A1 | N-GLYCOSYLATION OF PEPTIDES AND PROTEINS | ISIS INNOVATION LIMITED (GB) | 2015-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160257983-A1 | N-GLYCOSYLATION OF PEPTIDES AND PROTEINS | PTMS, PGLS, PSPH | ALDH1A1 4736/4885ALOX15 4287/4885KMT2A 4691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.