Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | FNTA | P49354 | 8/20 | 0.48 |
| ▸ | FNTB | P49356 | 6/20 | 0.48 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.44 |
| ▸ | SQLE | Q14534 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17681470 | 1.00 | ALDH1A1 (0.50) | ALDH1A1ALOX15KMT2AFNTAFNTB | |
| SCHEMBL4461666 | 0.89 | ALDH1A1 (0.58) | ALDH1A1ALOX15KMT2AFNTAFNTB | |
| SCHEMBL16664314 | 0.87 | ALDH1A1 (0.56) | ALDH1A1ALOX15KMT2AFNTAFNTB | |
| SCHEMBL27740873 | 0.87 | ALDH1A1 (0.56) | ALDH1A1ALOX15KMT2AFNTAFNTB | |
| SCHEMBL29748905 | 0.85 | ALDH1A1 (0.58) | ALDH1A1ALOX15KMT2AFNTAFNTB | |
| SCHEMBL31166044 | 0.83 | ALDH1A1 (0.51) | ALDH1A1ALOX15KMT2AFNTAFNTB | |
| SCHEMBL31166045 | 0.83 | ALDH1A1 (0.51) | ALDH1A1ALOX15KMT2AFNTAFNTB | |
| Squalene SCHEMBL9405154 | 0.75 | KMT2A (0.77) | ALDH1A1ALOX15KMT2AFNTAFNTB | |
| Squalene SCHEMBL9405151 | 0.75 | KMT2A (0.77) | ALDH1A1ALOX15KMT2AFNTAFNTB | |
| SCHEMBL9629657 | 0.74 | ALOX15 (0.53) | ALDH1A1ALOX15KMT2AFNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7833748-B1 | reacting OsKSL11 with a syn-copalyl diphosphate to produce a stemodene; isolation, purification, sequencing, and functional characterization of the class I diterpene synthase sequence OsKSL11 | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2010-11-16 | — | — | US | disclosed |
| US-7525016-B1 | Identification of syn-copalyl diphosphate synthase | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2009-04-28 | — | — | US | disclosed |