Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13136831 | 0.91 | SIGMAR1 (0.42) | RAPGEF4SIGMAR1NPC1JAK2ALDH1A1 | |
| SCHEMBL20030125 | 0.89 | SIGMAR1 (0.43) | RAPGEF4SIGMAR1NPC1JAK2ALDH1A1 | |
| SCHEMBL25770671 | 0.87 | SIGMAR1 (0.46) | RAPGEF4SIGMAR1NPC1JAK2ALDH1A1 | |
| SCHEMBL13479421 | 0.87 | SIGMAR1 (0.42) | RAPGEF4SIGMAR1NPC1JAK2ALDH1A1 | |
| SCHEMBL12938559 | 0.87 | ACHE (0.42) | SIGMAR1NPC1JAK2ALDH1A1HTT | |
| SCHEMBL11331009 | 0.87 | ACHE (0.42) | SIGMAR1NPC1JAK2ALDH1A1HTT | |
| SCHEMBL30451157 | 0.87 | ACHE (0.42) | SIGMAR1NPC1JAK2ALDH1A1HTT | |
| SCHEMBL1858399 | 0.86 | BCL2 (0.41) | RAPGEF4SIGMAR1NPC1JAK2ALDH1A1 | |
| SCHEMBL13049541 | 0.85 | ALDH1A1 (0.39) | SIGMAR1NPC1JAK2ALDH1A1HTT | |
| SCHEMBL11335607 | 0.85 | ACHE (0.38) | SIGMAR1NPC1ALDH1A1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1653784-B1 | ORGANIC ELECTROLUMINESCENT DEVICE, ILLUMINATING DEVICE, AND DISPLAY | KONICA MINOLTA HOLDINGS INC (JP) | 2015-04-22 | — | — | EP | disclosed |