Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17685341 | 0.93 | PIK3CD (0.33) | ALDH1A1KDM4ENR1H4SLC6A9 | |
| SCHEMBL11805 | 0.93 | PIK3CD (0.33) | ALDH1A1KDM4ENR1H4SLC6A9 | |
| SCHEMBL19277215 | 0.86 | HSD17B10 (0.34) | ALDH1A1KDM4EKDM2B | |
| SCHEMBL1340689 | 0.83 | RIPK1 (0.35) | ALDH1A1KDM4E | |
| SCHEMBL1341780 | 0.83 | CES2 (0.39) | ALDH1A1KDM4E | |
| SCHEMBL27149664 | 0.82 | HSD17B10 (0.40) | ALDH1A1KDM4E | |
| SCHEMBL1515804 | 0.82 | HSD17B10 (0.40) | ALDH1A1KDM4E | |
| SCHEMBL31696657 | 0.82 | HSD17B10 (0.40) | ALDH1A1KDM4E | |
| SCHEMBL13543609 | 0.81 | CES2 (0.42) | ALDH1A1KDM4ENR1H4 | |
| SCHEMBL18573688 | 0.81 | CES2 (0.42) | ALDH1A1KDM4ENR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015057205-A1 | METHYLENE LINKED QUINOLINYL MODULATORS OF ROR-GAMMA-T | JANSSEN PHARMACEUTICA NV (BE) | 2015-04-23 | — | — | WO | disclosed |