SCHEMBL1666609

SCHEMBL1666609

C[SiH](C)O[Si](C)(C)C(O)CCO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7907245 0.88
SCHEMBL3905017 0.83
SCHEMBL3462954 0.74
SCHEMBL10817515 0.73 THRB (0.36)
SCHEMBL9042804 0.71
SCHEMBL27613015 0.68
SCHEMBL11669868 0.65 THRB (0.32)
SCHEMBL1666610 0.65
SCHEMBL4229250 0.64
SCHEMBL6664579 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1809344-B2 BIOMEDICAL DEVICES CONTAINING AMPHIPHILIC BLOCK COPOLYMERS JOHNSON & JOHNSON VISION CARE (US) 2016-08-10 EP claimed
EP-1809344-B1 BIOMEDICAL DEVICES CONTAINING AMPHIPHILIC BLOCK COPOLYMERS JOHNSON & JOHNSON VISION CARE (US) 2010-01-20 EP claimed
EP-1809344-A2 BIOMEDICAL DEVICES CONTAINING AMPHIPHILIC BLOCK COPOLYMERS Johnson and Johnson Vision Care, Inc. (US) 2007-07-25 EP claimed
US-7247692-B2 Biomedical devices containing amphiphilic block copolymers JOHNSON & JOHNSON VISION CARE, INC. (US) 2007-07-24 US claimed
WO-2006039467-A2 BIOMEDICAL DEVICES CONTAINING AMPHIPHILIC BLOCK COPOLYMERS JOHNSON & JOHNSON VISION CARE, INC. (US) 2006-04-13 WO claimed
US-20060074208-A1 Biomedical devices containing amphiphilic block copolymers JOHNSON & JOHNSON VISION CARE, INC. 2006-04-06 US claimed
CN-110177822-B Synthesis of polycarbonate siloxane diol 奥特克国际公开有限公司 2022-06-14 CN disclosed
CN-114479651-A Self-repairable UV (ultraviolet) photocureable coating and preparation method thereof 山东灵晓新材料有限公司 2022-05-13 CN disclosed
EP-3302589-B1 PROCESS FOR THE PREPARATION OF POLYURETHANE SOLUTIONS BASED ON SILICON-POLYCARBONATE DIOLS RUA LIFE SCIENCES PLC (GB) 2021-08-11 EP disclosed
CN-113150283-A Fluorosilicone polymer capable of being subjected to UV light and thermal curing, preparation method thereof and coating 哈尔滨工业大学无锡新材料研究院 2021-07-23 CN disclosed
US-10730994-B2 Synthesis of polycarbonate siloxane diols AORTECH INTERNATIONAL PLC (GB) 2020-08-04 US disclosed
US-10655012-B2 Process for the preparation of polyurethane solutions based on silicon-polycarbonate diols AORTECH INTERNATIONAL PLC (GB) 2020-05-19 US disclosed
US-20200032055-A1 PROCESS FOR THE PREPARATION OF POLYURETHANE SOLUTIONS BASED ON SILICONPOLYCARBONATE DIOLS AORTECH INTERNATIONAL PLC (GB) 2020-01-30 US disclosed
EP-1809344-B1 BIOMEDICAL DEVICES CONTAINING AMPHIPHILIC BLOCK COPOLYMERS JOHNSON & JOHNSON VISION CARE (US) 2010-01-20 EP disclosed
US-7247692-B2 Biomedical devices containing amphiphilic block copolymers JOHNSON & JOHNSON VISION CARE, INC. (US) 2007-07-24 US disclosed
US-7026423-B2 Silicon-based polycarbonates AORTECH BIOMATERIALS PTY LTD. (AU) 2006-04-11 US disclosed
US-20060074208-A1 Biomedical devices containing amphiphilic block copolymers JOHNSON & JOHNSON VISION CARE, INC. 2006-04-06 US disclosed
US-20030092864-A1 Silicon-based polycarbonates AORTECH BIOMATERIALS PTY LTD. 2003-05-15 US disclosed
EP-0984997-B1 SILICON-BASED POLYCARBONATES AORTECH BIOMATERIALS PTY LTD (AU) 2002-09-18 EP disclosed
US-6437073-B1 Non-elastomeric polyurethane compositions AORTECH BIOMATERIALS PTY LTD. (AU) 2002-08-20 US disclosed