SCHEMBL1666685

SCHEMBL1666685

CC(=O)c1c(C(C)=O)c(C(C)=O)c2cc3cc4cc5ccccc5cc4cc3cc2c1C(C)=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.45
ALDH1A1 P00352 4/20 0.45
HPGD P15428 3/20 0.45
CYP1A2 P05177 3/20 0.45
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
HSD17B10 Q99714 2/20 0.45
CYP2C19 P33261 2/20 0.45
GLA P06280 1/20 0.45
GAA P10253 2/20 0.44
MAPT P10636 2/20 0.43
THRB P10828 1/20 0.40
TP53 P04637 1/20 0.40
NCEH1 Q6PIU2 1/20 0.39
NQO1 P15559 1/20 0.38
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
BRD4 O60885 1/20 0.37
CA12 O43570 1/20 0.37
NT5E P21589 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1666690 1.00 KDM4E (0.45) KDM4EALDH1A1HPGDCYP1A2MEN1
SCHEMBL1667157 0.96 ALDH1A1 (0.46) KDM4EALDH1A1HPGDCYP1A2MEN1
SCHEMBL1666583 0.83 KDM4E (0.42) KDM4EALDH1A1HPGDCYP1A2MEN1
SCHEMBL1666574 0.83 KDM4E (0.42) KDM4EALDH1A1HPGDCYP1A2MEN1
SCHEMBL1667077 0.81 KDM4E (0.44) KDM4EALDH1A1HPGDCYP1A2MEN1
SCHEMBL1667139 0.80 KDM4E (0.46) KDM4EALDH1A1HPGDCYP1A2MEN1
SCHEMBL1669176 0.80 KDM4E (0.46) KDM4EALDH1A1HPGDCYP1A2MEN1
SCHEMBL67303 0.78 ALDH1A1 (0.65) KDM4EALDH1A1HPGDCYP1A2MEN1
SCHEMBL29491183 0.78 ALDH1A1 (0.65) KDM4EALDH1A1HPGDCYP1A2MEN1
SCHEMBL3707483 0.78 ALDH1A1 (0.44) KDM4EALDH1A1HPGDCYP1A2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1830228-B1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION MITSUBISHI GAS CHEMICAL CO (JP) 2015-08-05 EP disclosed
EP-2808736-A2 Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2014-12-03 EP disclosed
US-8802353-B2 Compound for resist and radiation-sensitive composition specification MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2014-08-12 US disclosed
EP-2662727-A2 Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2013-11-13 EP disclosed
US-8350096-B2 Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2013-01-08 US disclosed
US-20130004896-A1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION SPECIFICATION ECHIGO MASATOSHI (JP) 2013-01-03 US disclosed
US-20110165516-A1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION ECHIGO MASATOSHI 2011-07-07 US disclosed
US-7919223-B2 Polyphenol compound synthesized by condensation between aromatic ketone or aldehyde and a phenol; acid-amplified, non-polymeric resist; highly sensitive to KrF excimer lasers, extreme ultraviolet rays, electron beams, X-rays; resist patterns with high resolution, high heat, etch resistance MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2011-04-05 US disclosed
US-20080113294-A1 Compound for Resist and Radiation-Sensitive Composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2008-05-15 US disclosed
EP-1830228-A1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2007-09-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110165516-A1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION XRCC6, XRCC5, KISS1R KDM4E 18/4885ALDH1A1 1170/4885HPGD 3116/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.