Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.80 |
| ▸ | ARG2 | P78540 | 4/20 | 0.50 |
| ▸ | ARG1 | P05089 | 3/20 | 0.50 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | OTC | P00480 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 3/20 | 0.44 |
| ▸ | NOS3 | P29474 | 2/20 | 0.44 |
| ▸ | NOS1 | P29475 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL1666691 | 1.00 | GSR (0.80) | GSRARG2ARG1RNPEPPOLB | |
| Lysine SCHEMBL29050532 | 0.96 | GSR (0.74) | GSRARG2ARG1RNPEPPOLB | |
| Lysine SCHEMBL1666689 | 0.96 | GSR (0.74) | GSRARG2ARG1RNPEPPOLB | |
| Lysine SCHEMBL28434271 | 0.96 | GSR (0.80) | GSRARG2ARG1RNPEPPOLB | |
| Lysine SCHEMBL27632944 | 0.96 | GSR (0.80) | GSRARG2ARG1RNPEPPOLB | |
| Lysine SCHEMBL27653586 | 0.92 | GSR (0.74) | GSRARG2ARG1RNPEPPOLB | |
| Lysine SCHEMBL30839526 | 0.92 | GSR (0.74) | GSRARG2ARG1RNPEPPOLB | |
| Lysine SCHEMBL11801558 | 0.92 | GSR (0.74) | GSRARG2ARG1RNPEPPOLB | |
| Lysine SCHEMBL28010048 | 0.91 | GSR (0.71) | GSRARG2ARG1RNPEPOTC | |
| Lysine SCHEMBL27494734 | 0.90 | GSR (0.77) | GSRARG2ARG1RNPEPPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6238727-B1 | MIXING LYSINE MAGNESIUM PHOSPHATE, MAGNESIUM OXIDE, BINDER AND WATER; EXTRUSION; GRANULATION | AJINOMOTO, CO., INC. (JP) | 2001-05-29 | — | — | US | claimed |
| EP-0940088-A2 | Ruminant feed additive composition and process for producing the same | Ajinomoto Co., Inc. (JP) | 1999-09-08 | — | — | EP | claimed |
| JP-10120638-A | — | — | None | — | — | JP | disclosed |
| JP-11243871-A | — | — | None | — | — | JP | disclosed |
| JP-11346670-A | — | — | None | — | — | JP | disclosed |
| EP-3766361-B1 | ANIMAL FEED ADDITIVE AND ANIMAL FEED | AJINOMOTO KK (JP) | 2023-11-01 | — | — | EP | disclosed |
| WO-2011041083-A1 | AGGLOMERATES CONTAINING ONE OR MORE BIOLOGICAL AGENTS AND METHODS FOR PRODUCING THE SAME | PROVIMI NORTH AMERICA, INC. (US) | 2011-04-07 | — | — | WO | disclosed |
| EP-1791532-B1 | COMPOSITION IN MICRO-PELLETS WITH CONTROLLED RELEASE OF PHYSIOLOGICALLY ACTIVE SUBSTANCES, PROCEDURE FOR THEIR PREPARATION AND USE IN THE ZOOTECHNICAL SECTOR | VALENTINI S R L (IT) | 2010-05-19 | — | — | EP | disclosed |
| US-20080044516-A1 | Granules of Hydrophilic Active Principle | ADISSEO FRANCE S.A.S. (FR) | 2008-02-21 | — | — | US | disclosed |
| WO-2004080197-A2 | RUMEN BYPASS ANIMAL FEED AND METHOD OF PRODUCING THE SAME | PETCAVICH ROBERT JOHN (US) | 2004-09-23 | — | — | WO | disclosed |
| EP-1405570-A1 | Process for producing ruminant feed additive composition | Ajinomoto Co., Inc. (JP) | 2004-04-07 | — | — | EP | disclosed |
| US-6238727-B1 | MIXING LYSINE MAGNESIUM PHOSPHATE, MAGNESIUM OXIDE, BINDER AND WATER; EXTRUSION; GRANULATION | AJINOMOTO, CO., INC. (JP) | 2001-05-29 | — | — | US | disclosed |
| US-6238727-B1 | MIXING LYSINE MAGNESIUM PHOSPHATE, MAGNESIUM OXIDE, BINDER AND WATER; EXTRUSION; GRANULATION | AJINOMOTO, CO., INC. (JP) | 2001-05-29 | — | — | US | disclosed |
| JP-H11346670-A | PRODUCTION OF FEED ADDITIVE COMPOSITION FOR RUMINANT | AJINOMOTO CO INC | 1999-12-21 | — | — | JP | disclosed |
| EP-0940088-A3 | Ruminant feed additive composition and process for producing the same | Ajinomoto Co., Inc. (JP) | 1999-12-15 | — | — | EP | disclosed |
| JP-H11243871-A | FEED ADDITIVE COMPOSITION FOR RUMINANT AND ITS PRODUCTION | AJINOMOTO CO INC | 1999-09-14 | — | — | JP | disclosed |
| EP-0940088-A2 | Ruminant feed additive composition and process for producing the same | Ajinomoto Co., Inc. (JP) | 1999-09-08 | — | — | EP | disclosed |
| EP-0940088-A2 | Ruminant feed additive composition and process for producing the same | Ajinomoto Co., Inc. (JP) | 1999-09-08 | — | — | EP | disclosed |
| JP-H10120638-A | AGGLOMERATED CRYSTAL OF LYSINE MAGNESIUM PHOSPHATE DOUBLE SALT AND ITS PRODUCTION | AJINOMOTO CO INC | 1998-05-12 | — | — | JP | disclosed |