Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.71 |
| ▸ | ARG2 | P78540 | 4/20 | 0.49 |
| ▸ | ARG1 | P05089 | 3/20 | 0.46 |
| ▸ | OTC | P00480 | 1/20 | 0.45 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | GLUL | P15104 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL27653586 | 0.98 | GSR (0.74) | GSRARG2ARG1OTCRNPEP | |
| Lysine SCHEMBL30839526 | 0.98 | GSR (0.74) | GSRARG2ARG1OTCRNPEP | |
| Lysine SCHEMBL1666689 | 0.95 | GSR (0.74) | GSRARG2ARG1OTCRNPEP | |
| Lysine SCHEMBL28434271 | 0.94 | GSR (0.80) | GSRARG2ARG1OTCRNPEP | |
| Lysine SCHEMBL27632944 | 0.94 | GSR (0.80) | GSRARG2ARG1OTCRNPEP | |
| Lysine SCHEMBL27996305 | 0.93 | GSR (0.67) | GSRARG2ARG1OTCBLM | |
| Lysine SCHEMBL11801558 | 0.91 | GSR (0.74) | GSRARG2ARG1OTCRNPEP | |
| Lysine SCHEMBL29050532 | 0.91 | GSR (0.74) | GSRARG2ARG1OTCRNPEP | |
| Lysine SCHEMBL1666693 | 0.91 | GSR (0.80) | GSRARG2ARG1OTCRNPEP | |
| Lysine SCHEMBL1666691 | 0.91 | GSR (0.80) | GSRARG2ARG1OTCRNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114306383-A | Growth-promoting pharmaceutical composition for improving solubility of calcium hydrogen phosphate and preparation process thereof | 吉林大学 | 2022-04-12 | — | — | CN | disclosed |
| CN-104688774-A | Lysine and calcium hydrophosphate pharmaceutical composition comprising chiral isomeric compound and application of pharmaceutical composition | HU LIFANG | 2015-06-10 | — | — | CN | disclosed |