Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.80 |
| ▸ | ARG2 | P78540 | 4/20 | 0.50 |
| ▸ | ARG1 | P05089 | 3/20 | 0.50 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | OTC | P00480 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 3/20 | 0.44 |
| ▸ | NOS3 | P29474 | 2/20 | 0.44 |
| ▸ | NOS1 | P29475 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL27632944 | 1.00 | GSR (0.80) | GSRARG2ARG1RNPEPPOLB | |
| Lysine SCHEMBL30839526 | 0.96 | GSR (0.74) | GSRARG2ARG1RNPEPPOLB | |
| Lysine SCHEMBL27653586 | 0.96 | GSR (0.74) | GSRARG2ARG1RNPEPPOLB | |
| Lysine SCHEMBL1666691 | 0.96 | GSR (0.80) | GSRARG2ARG1RNPEPPOLB | |
| Lysine SCHEMBL1666693 | 0.96 | GSR (0.80) | GSRARG2ARG1RNPEPPOLB | |
| Lysine SCHEMBL28010048 | 0.94 | GSR (0.71) | GSRARG2ARG1RNPEPOTC | |
| Lysine SCHEMBL11801558 | 0.92 | GSR (0.74) | GSRARG2ARG1RNPEPPOLB | |
| Lysine SCHEMBL29050532 | 0.92 | GSR (0.74) | GSRARG2ARG1RNPEPPOLB | |
| Lysine SCHEMBL1666689 | 0.92 | GSR (0.74) | GSRARG2ARG1RNPEPPOLB | |
| Lysine SCHEMBL28980896 | 0.92 | GSR (0.95) | GSRARG2ARG1RNPEPNOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111548078-A | Cement mortar and preparation method thereof | 重庆知翔科技有限公司 | 2020-08-18 | — | — | CN | disclosed |