Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL22788463 | 0.86 | KDM4E (0.39) | TP53SLC7A5KMT2AATMCA12 | |
| Acetic Acid SCHEMBL7780427 | 0.86 | KDM4E (0.39) | TP53SLC7A5KMT2AATMCA12 | |
| Hydrogen Peroxide SCHEMBL28243254 | 0.86 | TSHR (0.41) | TP53KMT2AATMCA12CA1 | |
| SCHEMBL7099055 | 0.83 | TSHR (0.44) | KMT2AATMCA12CA1CA2 | |
| SCHEMBL8908158 | 0.83 | TSHR (0.44) | KMT2AATMCA12CA1CA2 | |
| SCHEMBL7099123 | 0.83 | TSHR (0.44) | KMT2AATMCA12CA1CA2 | |
| SCHEMBL28985 | 0.83 | TSHR (0.44) | KMT2AATMCA12CA1CA2 | |
| Succinic Acid SCHEMBL8005658 | 0.82 | LMNA (0.45) | KDM4E | |
| L-Lactic Acid SCHEMBL2392009 | 0.80 | CA1 (0.36) | TP53KMT2AATMCA12CA1 | |
| Glycine SCHEMBL28240235 | 0.80 | GLRA1 (0.48) | TP53SLC7A5KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3824883-B1 | NOVEL COMPOSITION FOR PLASTER BASE MATERIAL IN TAPE PREPARATION | MEDRX CO LTD (JP) | 2023-08-02 | — | — | EP | claimed |
| EP-2865376-B2 | ADHESIVE PREPARATION COMPOSITION OBTAINED BY BLENDING DRUG, ORGANIC SOLVENT, LIPOPHILIC OINTMENT BASE, AND POWDER | MEDRX CO LTD (JP) | 2022-05-11 | — | — | EP | claimed |
| US-20210346311-A1 | Base Composition for Tape Agent | MEDRX CO., LTD. (JP) | 2021-11-11 | — | — | US | claimed |
| EP-3824883-A1 | NOVEL COMPOSITION FOR PLASTER BASE MATERIAL IN TAPE PREPARATION | MEDRx Co., Ltd. (JP) | 2021-05-26 | — | — | EP | claimed |
| EP-3045166-B1 | NOVEL BASE COMPOSITION FOR TAPE AGENT | MEDRX CO LTD (JP) | 2020-12-16 | — | — | EP | claimed |
| CN-105744931-B | Novel composition for base material of paste in adhesive tape preparation | 美德阿利克斯株式会社 | 2020-03-10 | — | — | CN | claimed |
| US-10543275-B2 | Composition for patch preparation comprising drug, organic solvent, lipophilic mass base, and powder | MEDRX CO., LTD. (JP) | 2020-01-28 | — | — | US | claimed |
| CN-110693859-A | Adhesive preparation composition obtained by blending drug, organic solvent, lipophilic base and powder | 美德阿利克斯株式会社 | 2020-01-17 | — | — | CN | claimed |
| EP-2865376-B1 | ADHESIVE PREPARATION COMPOSITION OBTAINED BY BLENDING DRUG, ORGANIC SOLVENT, LIPOPHILIC OINTMENT BASE, AND POWDER | MEDRX CO LTD (JP) | 2019-06-05 | — | — | EP | claimed |
| US-20180325837-A1 | Base Composition for Tape Agent | MEDRX CO., LTD. (JP) | 2018-11-15 | — | — | US | claimed |
| US-9980920-B2 | Base composition for tape agent | MEDRX CO., LTD. (JP) | 2018-05-29 | — | — | US | claimed |
| US-20160220506-A1 | Base Composition for Tape Agent | MEDRX CO., LTD. (JP) | 2016-08-04 | — | — | US | claimed |
| US-20150174249-A1 | Composition for Patch Preparation Comprising Drug, Organic Solvent, Lipophilic Mass Base, and Powder | MEDRX CO., LTD. (JP) | 2015-06-25 | — | — | US | claimed |
| EP-2865376-A1 | ADHESIVE PREPARATION COMPOSITION OBTAINED BY BLENDING DRUG, ORGANIC SOLVENT, LIPOPHILIC OINTMENT BASE, AND POWDER | Medrx Co., Ltd. (JP) | 2015-04-29 | — | — | EP | claimed |
| US-12016924-B2 | Composition for patch preparation comprising drug, organic solvent, lipophilic mass base, and powder | MEDRX CO., LTD. (JP) | 2024-06-25 | — | — | US | disclosed |
| EP-3824883-B1 | NOVEL COMPOSITION FOR PLASTER BASE MATERIAL IN TAPE PREPARATION | MEDRX CO LTD (JP) | 2023-08-02 | — | — | EP | disclosed |
| US-20230122491-A1 | Base Composition for Tape Agent | MEDRX CO., LTD. (JP) | 2023-04-20 | — | — | US | disclosed |
| EP-3045166-A1 | NOVEL BASE COMPOSITION FOR TAPE AGENT | MEDRx Co., Ltd. (JP) | 2016-07-20 | — | — | EP | disclosed |
| US-20150174249-A1 | Composition for Patch Preparation Comprising Drug, Organic Solvent, Lipophilic Mass Base, and Powder | MEDRX CO., LTD. (JP) | 2015-06-25 | — | — | US | disclosed |
| EP-2865376-A1 | ADHESIVE PREPARATION COMPOSITION OBTAINED BY BLENDING DRUG, ORGANIC SOLVENT, LIPOPHILIC OINTMENT BASE, AND POWDER | Medrx Co., Ltd. (JP) | 2015-04-29 | — | — | EP | disclosed |