Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL22788463 | 1.00 | KDM4E (0.39) | KDM4EFFAR3LCKFYNTP53 | |
| Hydrogen Peroxide SCHEMBL28243254 | 0.88 | TSHR (0.41) | KDM4ETP53CA12CA1CA2 | |
| Lactic Acid SCHEMBL16667262 | 0.86 | TP53 (0.58) | KDM4ETP53CA12CA1CA2 | |
| SCHEMBL28985 | 0.85 | TSHR (0.44) | KDM4ECA12CA1CA2CA9 | |
| SCHEMBL7099123 | 0.85 | TSHR (0.44) | KDM4ECA12CA1CA2CA9 | |
| SCHEMBL8908158 | 0.85 | TSHR (0.44) | KDM4ECA12CA1CA2CA9 | |
| SCHEMBL7099055 | 0.85 | TSHR (0.44) | KDM4ECA12CA1CA2CA9 | |
| Succinic Acid SCHEMBL8005658 | 0.84 | LMNA (0.45) | KDM4EFFAR3ALDH1A1 | |
| Glycine SCHEMBL28240235 | 0.82 | GLRA1 (0.48) | TP53KMT2AATMSLC7A5 | |
| Fluoride SCHEMBL6864685 | 0.82 | TSHR (0.41) | KDM4ECA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117542726-A | Semiconductor device cleaning method and semiconductor device | 粤芯半导体技术股份有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-115448625-B | Grinding aid for improving high-alkaline cement performance and preparation method thereof | 华新水泥股份有限公司 | 2023-05-30 | — | — | CN | disclosed |
| CN-115448625-A | Grinding aid for improving performance of high-alkali cement and preparation method thereof | 华新水泥股份有限公司 | 2022-12-09 | — | — | CN | disclosed |
| CN-111470796-B | Cement grinding aid | 辽宁天宝华瑞建材有限公司 | 2022-03-15 | — | — | CN | disclosed |
| CN-111470796-A | Cement grinding aid | 辽宁天宝华瑞建材有限公司 | 2020-07-31 | — | — | CN | disclosed |
| EP-0830341-B1 | PROCESSES FOR THE PREPARATION OF 3-(METHYLTHIO)PROPANAL AND 2-HYDROXY-4-(METHYLTHIO)BUTANENITRILE | NOVUS INT INC (US) | 2001-09-05 | — | — | EP | disclosed |
| EP-0830341-A1 | PROCESSES FOR THE PREPARATION OF 3-(METHYLTHIO)PROPANAL AND 2-HYDROXY-4-(METHYLTHIO)BUTANENITRILE | Novus International, Inc. (US) | 1998-03-25 | — | — | EP | disclosed |
| WO-1996040631-A1 | PROCESSES FOR THE PREPARATION OF 3-(METHYLTHIO)PROPANAL AND 2-HYDROXY-4-(METHYLTHIO)BUTANENITRILE | NOVUS INTERNATIONAL, INC. (US) | 1996-12-19 | — | — | WO | disclosed |
| EP-0555090-A1 | Processing additive for high pressure roll press for forming finished ground cement from clinker | W.R. Grace & Co.-Conn. (US) | 1993-08-11 | — | — | EP | disclosed |