SCHEMBL5481563

SCHEMBL5481563

C=C(C)C(=O)OCCC[Si](OCC)(OCC)OCC.C=CCCCCCC[Si](OC)(OC)OC

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.43
THRB P10828 1/20 0.38
ALDH1A1 P00352 3/20 0.35
LMNA P02545 2/20 0.35
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
HTT P42858 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
USP2 O75604 2/20 0.32
CYP3A4 P08684 2/20 0.32
MAPT P10636 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
RECQL P46063 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4440431 0.89 TSHR (0.51) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL2577166 0.89 TSHR (0.50) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL16667448 0.88 TSHR (0.59) TSHRTHRBALDH1A1LMNAPOLB
SCHEMBL424597 0.85 TSHR (0.44) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL5080728 0.85 TSHR (0.44) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL6654168 0.85 TSHR (0.41) TSHRTHRBALDH1A1LMNAPOLB
SCHEMBL3417371 0.85 TSHR (0.51) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL1643136 0.85 TSHR (0.51) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL8901734 0.84 TSHR (0.45) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL11030313 0.83 TSHR (0.42) TSHRTHRBALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070128490-A1 Proton exchange membranes (PEM) based on hybrid inorganic-organic copolymers with grafted phosphoric acid groups and implanted metal cations TOYOTA MOTOR CORPORATION (JP) 2007-06-07 US disclosed
EP-1747600-A2 PROTON EXCHANGE MEMBRANE (PEM) BASED ON HYBRID INORGANIC-ORGANIC COPOLYMERS WITH GRAFTED PHOSPHORIC ACID GROUPS AND IMPLANTED METAL CATIONS Toyota Technical Center, U.S.A., Inc. (US) 2007-01-31 EP disclosed
WO-2005114772-A2 PROTON EXCHANGE MEMBRANE (PEM) BASED ON HYBRID INORGANIC-ORGANIC COPOLYMERS WITH GRAFTED PHOSPHORIC ACID GROUPS AND IMPLANTED METAL CATIONS TOYOTA TECHNICAL CENTER USA, INC. (US) 2005-12-01 WO disclosed
WO-2005001037-A2 ELECTROLYTE MEMBRANES BASED ON ALKYLOXYSILANE GRAFTED THERMOPLASTIC POLYMERS TOYOTA TECHNICAL CENTER, USA, INC. (US) 2005-01-06 WO disclosed