SCHEMBL5900537

SCHEMBL5900537

CC1CNCCN1CC([NH])=O

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.32
CHRM5 P08912 1/20 0.31
CHRM3 P20309 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5156687 0.84 SLC6A9 (0.41) DPP4
SCHEMBL1666880 0.84 DPP4 (0.33) DPP4CHRM5CHRM3
Hydrochloric Acid SCHEMBL28060538 0.82 SLC6A9 (0.40) DPP4
Hydrochloric Acid SCHEMBL3182976 0.81 DPP4 (0.34) DPP4CHRM5CHRM3
Hydrochloric Acid SCHEMBL3182984 0.81 DPP4 (0.34) DPP4CHRM5CHRM3
SCHEMBL27841937 0.79
SCHEMBL28129002 0.79
SCHEMBL28131298 0.79
SCHEMBL21649396 0.79 CHRM5 (0.33) DPP4CHRM5CHRM3
SCHEMBL13812252 0.78 BIRC2 (0.49) DPP4CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060128684-A1 Anthranilic acid amide derivatives and their pharmaceutical use BOLD GUIDO 2006-06-15 US claimed
EP-1572686-A1 ANTHRANILIC ACID AMIDE DERIVATIVES AND THEIR PHARMACEUTICAL USE Novartis AG (CH) 2005-09-14 EP claimed
WO-2004052884-A1 ANTHRANILIC ACID AMIDE DERIVATIVES AND THEIR PHARMACEUTICAL USE NOVARTIS AG (CH) 2004-06-24 WO claimed
US-20060128684-A1 Anthranilic acid amide derivatives and their pharmaceutical use BOLD GUIDO 2006-06-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060128684-A1 Anthranilic acid amide derivatives and their pharmaceutical use AADAC, AADAT, NAAA DPP4 744/4885CHRM5 3399/4885CHRM3 3797/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.