Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.37 |
| ▸ | PARP11 | Q9NR21 | 3/20 | 0.37 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31395276 | 0.79 | KDM4E (0.38) | KDM4EALDH1A1PLA2G1BATG4BLMNA | |
| SCHEMBL23160411 | 0.78 | KDM4E (0.57) | KDM4EALDH1A1CA9LMNAMAPT | |
| SCHEMBL1666332 | 0.78 | KDM4E (0.57) | KDM4ETDP1GSK3BMAPTIDO1 | |
| SCHEMBL23175227 | 0.77 | ALDH1A1 (0.43) | KDM4EALDH1A1PLA2G1BATG4BCA12 | |
| SCHEMBL23175233 | 0.76 | KDM4E (0.44) | KDM4EALDH1A1LMNATDP1GSK3B | |
| SCHEMBL1555141 | 0.74 | GAA (0.40) | KDM4EALDH1A1MAPTPARP1MEN1 | |
| SCHEMBL30303079 | 0.74 | GAA (0.40) | KDM4EALDH1A1MAPTPARP1MEN1 | |
| Hydrochloric Acid SCHEMBL31398582 | 0.73 | ALDH1A1 (0.46) | ALDH1A1PLA2G1BATG4BMAPTKMT2A | |
| SCHEMBL1711500 | 0.73 | ALDH1A1 (0.56) | KDM4EALDH1A1PLA2G1BATG4BLMNA | |
| SCHEMBL544297 | 0.73 | ALDH1A1 (0.60) | KDM4EALDH1A1MAPTGLANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024101965-A1 | PHARMACEUTICAL COMBINATION OF PRMT5 INHIBITOR AND DNA DAMAGE-INDUCING SUBSTANCE | 에스케이바이오팜 주식회사 | 2024-05-16 | — | — | WO | claimed |
| US-20260137700-A1 | PHARMACEUTICAL COMBINATION OF PRMT5 INHIBITOR AND DNA DAMAGE-INDUCING SUBSTANCE | SK BIOPHARMACEUTICALS CO LTD (KR) | 2026-05-21 | — | — | US | disclosed |
| WO-2025031842-A1 | NEW SUBSTITUTED BENZOXAZEPINE PICOLINONITRILE COMPOUNDS FOR COMBATTING PHYTOPATHOGENIC FUNGI | BASF SE (DE) | 2025-02-13 | — | — | WO | disclosed |
| US-20240051951-A1 | BICYCLIC COMPOUND AND USE THEREOF | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2024-02-15 | — | — | US | disclosed |
| US-11725001-B2 | Bicyclic compound and use thereof | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2023-08-15 | — | — | US | disclosed |
| US-20220402902-A1 | BICYCLIC COMPOUND AND USE THEREOF | SK BIOPHARMACEUTICALS CO., LTD. | 2022-12-22 | — | — | US | disclosed |
| EP-4039686-A1 | BICYCLIC COMPOUND AND USE THEREOF | SK Biopharmaceuticals Co., Ltd. (KR) | 2022-08-10 | — | — | EP | disclosed |
| WO-2021066578-A1 | BICYCLIC COMPOUND AND USE THEREOF | 에스케이바이오팜 주식회사 | 2021-04-08 | — | — | WO | disclosed |
| EP-2314583-B1 | NITROGENATED HETEROCYCLIC DERIVATIVE, AND AGRICULTURAL OR HORTICULTURAL BACTERICIDAL AGENT | NIPPON SODA CO (JP) | 2015-02-25 | — | — | EP | disclosed |
| US-8557738-B2 | Nitrogen-containing heterocyclic derivative and fungicide for agricultural and horticultural use | NIPPON SODA CO., LTD. (JP) | 2013-10-15 | — | — | US | disclosed |
| US-20110136782-A1 | NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE AND FUNGICIDE FOR AGRICULTURAL AND HORTICULTURAL USE | NIPPON SODA CO., LTD (JP) | 2011-06-09 | — | — | US | disclosed |
| EP-2314583-A1 | NITROGENATED HETEROCYCLIC DERIVATIVE, AND AGRICULTURAL OR HORTICULTURAL BACTERICIDAL AGENT | Nippon Soda Co., Ltd. (JP) | 2011-04-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220402902-A1 | BICYCLIC COMPOUND AND USE THEREOF | PRMT5, PRMT6, PRMT1 | KDM4E 44/4885ALDH1A1 3781/4885PLA2G1B 3478/4885 |
| US-20260137700-A1 | PHARMACEUTICAL COMBINATION OF PRMT5 INHIBITOR AND DNA DAMAGE-INDUCING SUBSTANCE | PRMT5, PRMT1, PRMT6 | KDM4E 327/4885ALDH1A1 3485/4885PLA2G1B 2240/4885 |
| US-20240051951-A1 | BICYCLIC COMPOUND AND USE THEREOF | PRMT5, PRMT6, PRMT1 | KDM4E 44/4885ALDH1A1 3781/4885PLA2G1B 3478/4885 |
| US-11725001-B2 | Bicyclic compound and use thereof | PRMT5, PRMT6, PRMT1 | KDM4E 44/4885ALDH1A1 3781/4885PLA2G1B 3478/4885 |
| US-20110136782-A1 | NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE AND FUNGICIDE FOR AGRICULTURAL AND HORTICULTURAL USE | CBR3, NOS1, CBR1 | KDM4E 1580/4885ALDH1A1 2698/4885PLA2G1B 4608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.