Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | ATM | Q13315 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 2/20 | 0.48 |
| ▸ | CASP7 | P55210 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.43 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.43 |
| ▸ | TYMS | P04818 | 2/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17283531 | 0.84 | ALDH1A1 (0.59) | ALDH1A1HSD17B10MAPK1TSHRATM | |
| SCHEMBL5008910 | 0.81 | ALDH1A1 (0.43) | ALDH1A1HSD17B10MAPK1TSHRATM | |
| SCHEMBL31713020 | 0.77 | CA1 (0.48) | ALDH1A1HSD17B10MAPK1L3MBTL1HPGD | |
| SCHEMBL23709241 | 0.76 | ALDH1A1 (0.65) | ALDH1A1HSD17B10MAPK1TSHRATM | |
| SCHEMBL19237177 | 0.75 | ALDH1A1 (0.46) | ALDH1A1HSD17B10MAPK1TSHRATM | |
| SCHEMBL7606252 | 0.75 | ALDH1A1 (0.46) | ALDH1A1HSD17B10MAPK1TSHRATM | |
| SCHEMBL4540171 | 0.74 | ALDH1A1 (0.56) | ALDH1A1HSD17B10MAPK1TSHRATM | |
| SCHEMBL24990981 | 0.74 | ALDH1A1 (0.56) | ALDH1A1HSD17B10MAPK1TSHRATM | |
| Ammonia Solution, Strong SCHEMBL27626211 | 0.74 | ALDH1A1 (0.81) | ALDH1A1HSD17B10MAPK1TSHRATM | |
| SCHEMBL2199764 | 0.74 | ALDH1A1 (0.56) | ALDH1A1HSD17B10MAPK1TSHRATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3368520-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2023-04-26 | — | — | EP | disclosed |
| US-11355714-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2022-06-07 | — | — | US | disclosed |
| US-20190058133-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2019-02-21 | — | — | US | disclosed |
| US-9876174-B2 | Electronic device including a fluoranthene derivative | E I DU PONT DE NEMOURS AND COMPANY (US) | 2018-01-23 | — | — | US | disclosed |
| US-9716233-B2 | Electronic device including a fluoranthene derivative | E I DU PONT DE NEMOURS AND COMPANY (US) | 2017-07-25 | — | — | US | disclosed |
| US-20170200900-A1 | ELECTRONIC DEVICE INCLUDING A FLUORANTHENE DERIVATIVE | LG CHEM, LTD. (KR) | 2017-07-13 | — | — | US | disclosed |
| US-20160268514-A1 | ELECTRONIC DEVICE INCLUDING A FLUORANTHENE DERIVATIVE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2016-09-15 | — | — | US | disclosed |
| WO-2015061074-A1 | ELECTRONIC DEVICE INCLUDING A FLUORANTHENE DERIVATIVE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2015-04-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160268514-A1 | ELECTRONIC DEVICE INCLUDING A FLUORANTHENE DERIVATIVE | NR0B1, AR, NR0B2 | ALDH1A1 921/4885HSD17B10 195/4885MAPK1 1952/4885 |
| US-11355714-B2 | Materials for organic electroluminescent devices | SLCO4C1, SLCO2A1, SLCO2B1 | ALDH1A1 1315/4885HSD17B10 2582/4885MAPK1 1572/4885 |
| US-20190058133-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | SLCO4C1, SLCO2A1, SLCO2B1 | ALDH1A1 1315/4885HSD17B10 2582/4885MAPK1 1572/4885 |
| US-20170200900-A1 | ELECTRONIC DEVICE INCLUDING A FLUORANTHENE DERIVATIVE | AR, CCND3, ESRRA | ALDH1A1 1666/4885HSD17B10 2400/4885MAPK1 1912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.