Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.42 |
| ▸ | CASP7 | P55210 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TYMS | P04818 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL728673 | 0.83 | ALDH1A1 (0.50) | ALDH1A1CES2BCHECES1MCL1 | |
| SCHEMBL75606 | 0.80 | ALDH1A1 (0.56) | ALDH1A1CES2BCHECES1MCL1 | |
| SCHEMBL29773784 | 0.80 | ALDH1A1 (0.56) | ALDH1A1CES2BCHECES1MCL1 | |
| SCHEMBL29316327 | 0.80 | ALDH1A1 (0.46) | ALDH1A1CES2BCHECES1MCL1 | |
| SCHEMBL29826290 | 0.77 | NPC1 (0.46) | ALDH1A1MAOBMAPTMEN1KMT2A | |
| SCHEMBL22837589 | 0.75 | ALDH1A1 (0.47) | ALDH1A1CES2BCHECES1MCL1 | |
| SCHEMBL14820740 | 0.75 | ALDH1A1 (0.48) | ALDH1A1CES2BCHECES1MCL1 | |
| SCHEMBL24079119 | 0.72 | ALDH1A1 (0.48) | ALDH1A1CES2BCHECES1MCL1 | |
| SCHEMBL28862846 | 0.72 | MAOB (0.42) | ALDH1A1MAOBCASP1CASP7MAPT | |
| SCHEMBL18845637 | 0.71 | ALDH1A1 (0.48) | ALDH1A1CES2BCHECES1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9876174-B2 | Electronic device including a fluoranthene derivative | E I DU PONT DE NEMOURS AND COMPANY (US) | 2018-01-23 | — | — | US | disclosed |
| US-9876174-B2 | Electronic device including a fluoranthene derivative | E I DU PONT DE NEMOURS AND COMPANY (US) | 2018-01-23 | — | — | US | disclosed |
| US-9876174-B2 | Electronic device including a fluoranthene derivative | E I DU PONT DE NEMOURS AND COMPANY (US) | 2018-01-23 | — | — | US | disclosed |
| US-9716233-B2 | Electronic device including a fluoranthene derivative | E I DU PONT DE NEMOURS AND COMPANY (US) | 2017-07-25 | — | — | US | disclosed |
| US-9716233-B2 | Electronic device including a fluoranthene derivative | E I DU PONT DE NEMOURS AND COMPANY (US) | 2017-07-25 | — | — | US | disclosed |
| US-9716233-B2 | Electronic device including a fluoranthene derivative | E I DU PONT DE NEMOURS AND COMPANY (US) | 2017-07-25 | — | — | US | disclosed |
| US-20170200900-A1 | ELECTRONIC DEVICE INCLUDING A FLUORANTHENE DERIVATIVE | LG CHEM, LTD. (KR) | 2017-07-13 | — | — | US | disclosed |
| US-20170200900-A1 | ELECTRONIC DEVICE INCLUDING A FLUORANTHENE DERIVATIVE | LG CHEM, LTD. (KR) | 2017-07-13 | — | — | US | disclosed |
| US-20170200900-A1 | ELECTRONIC DEVICE INCLUDING A FLUORANTHENE DERIVATIVE | LG CHEM, LTD. (KR) | 2017-07-13 | — | — | US | disclosed |
| US-20160268514-A1 | ELECTRONIC DEVICE INCLUDING A FLUORANTHENE DERIVATIVE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2016-09-15 | — | — | US | disclosed |
| US-20160268514-A1 | ELECTRONIC DEVICE INCLUDING A FLUORANTHENE DERIVATIVE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2016-09-15 | — | — | US | disclosed |
| US-20160268514-A1 | ELECTRONIC DEVICE INCLUDING A FLUORANTHENE DERIVATIVE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2016-09-15 | — | — | US | disclosed |
| WO-2015061074-A1 | ELECTRONIC DEVICE INCLUDING A FLUORANTHENE DERIVATIVE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2015-04-30 | — | — | WO | disclosed |
| WO-2015061074-A1 | ELECTRONIC DEVICE INCLUDING A FLUORANTHENE DERIVATIVE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2015-04-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160268514-A1 | ELECTRONIC DEVICE INCLUDING A FLUORANTHENE DERIVATIVE | NR0B1, AR, NR0B2 | ALDH1A1 921/4885CES2 3045/4885BCHE 4629/4885 |
| US-20170200900-A1 | ELECTRONIC DEVICE INCLUDING A FLUORANTHENE DERIVATIVE | AR, CCND3, ESRRA | ALDH1A1 1666/4885CES2 3775/4885BCHE 4633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.