SCHEMBL728673

SCHEMBL728673

O=C1C(c2ccc(Br)cc2)=C2C(=C1c1ccc(Br)cc1)c1cccc3cccc2c13

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.50
CES2 O00748 1/20 0.50
BCHE P06276 1/20 0.50
CES1 P23141 1/20 0.50
MCL1 Q07820 1/20 0.50
MAPT P10636 5/20 0.47
KDM4E B2RXH2 3/20 0.47
LMNA P02545 2/20 0.47
THRB P10828 1/20 0.47
HPGD P15428 1/20 0.47
PABPC1 P11940 3/20 0.44
DNMT1 P26358 2/20 0.44
CYP3A4 P08684 1/20 0.44
CASP1 P29466 1/20 0.44
CASP7 P55210 1/20 0.44
MEN1 O00255 4/20 0.44
KMT2A Q03164 4/20 0.44
MAPK1 P28482 3/20 0.44
NPSR1 Q6W5P4 2/20 0.44
MPI P34949 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL75606 0.83 ALDH1A1 (0.56) ALDH1A1CES2BCHECES1MCL1
SCHEMBL29773784 0.83 ALDH1A1 (0.56) ALDH1A1CES2BCHECES1MCL1
SCHEMBL16670536 0.83 ALDH1A1 (0.47) ALDH1A1CES2BCHECES1MCL1
SCHEMBL23348941 0.78 MCL1 (0.47) ALDH1A1CES2BCHECES1MCL1
SCHEMBL23084985 0.78 MAPT (0.53) ALDH1A1CES2BCHECES1MCL1
SCHEMBL4912423 0.76 CA2 (0.44) ALDH1A1CES2CES1MAPTKDM4E
SCHEMBL14820740 0.74 ALDH1A1 (0.48) ALDH1A1CES2BCHECES1MCL1
SCHEMBL18845637 0.74 ALDH1A1 (0.48) ALDH1A1CES2BCHECES1MCL1
SCHEMBL24809428 0.73 ALDH1A1 (0.56) ALDH1A1CES2BCHECES1MCL1
SCHEMBL4916317 0.72 ALDH1A1 (0.61) ALDH1A1MAPTKDM4ELMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10680182-B2 Fluoranthene compound, and organic electronic device comprising same LG CHEM, LTD. (KR) 2020-06-09 US disclosed
EP-2924020-B1 FLUORANTHENE COMPOUND, AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME LG CHEMICAL LTD (KR) 2019-01-16 EP disclosed
EP-2924020-A1 FLUORANTHENE COMPOUND, AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME LG Chem, Ltd. (KR) 2015-09-30 EP disclosed
US-20150236273-A1 FLUORANTHENE COMPOUND, AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2015-08-20 US disclosed
US-20150236273-A1 FLUORANTHENE COMPOUND, AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2015-08-20 US disclosed
US-8137822-B2 Synthesis of phenyl-substituted polyfluoroanthenes and the use thereof BASF AKTIENGESELLSCHAFT (DE) 2012-03-20 US disclosed
US-8137822-B2 Synthesis of phenyl-substituted polyfluoroanthenes and the use thereof BASF AKTIENGESELLSCHAFT (DE) 2012-03-20 US disclosed
US-8137822-B2 Synthesis of phenyl-substituted polyfluoroanthenes and the use thereof BASF AKTIENGESELLSCHAFT (DE) 2012-03-20 US disclosed
EP-1877518-B1 SYNTHESIS OF PHENYL-SUBSTITUTED POLYFLUOROANTHENES AND THE USE THEREOF BASF SE (DE) 2010-02-24 EP disclosed
EP-1877518-B1 SYNTHESIS OF PHENYL-SUBSTITUTED POLYFLUOROANTHENES AND THE USE THEREOF BASF SE (DE) 2010-02-24 EP disclosed
US-20080213623-A1 7,10-bis(acryloyl, styryl, or glycidyl-substituted phenyl)fluoranthene polymerized in the presence of a nickel or palladium catalyst; photopolymerized after applied to film substrate for organic light-emitting diodes; improved stability, high efficiency and quantum yield, emission maximum in blue region BASF AKTIENGESELLSCHAFT (DE) 2008-09-04 US disclosed
US-20080213623-A1 7,10-bis(acryloyl, styryl, or glycidyl-substituted phenyl)fluoranthene polymerized in the presence of a nickel or palladium catalyst; photopolymerized after applied to film substrate for organic light-emitting diodes; improved stability, high efficiency and quantum yield, emission maximum in blue region BASF AKTIENGESELLSCHAFT (DE) 2008-09-04 US disclosed
US-20080213623-A1 7,10-bis(acryloyl, styryl, or glycidyl-substituted phenyl)fluoranthene polymerized in the presence of a nickel or palladium catalyst; photopolymerized after applied to film substrate for organic light-emitting diodes; improved stability, high efficiency and quantum yield, emission maximum in blue region BASF AKTIENGESELLSCHAFT (DE) 2008-09-04 US disclosed
EP-1877518-A1 SYNTHESIS OF PHENYL-SUBSTITUTED POLYFLUOROANTHENES AND THE USE THEREOF BASF AKTIENGESELLSCHAFT (DE) 2008-01-16 EP disclosed
WO-2006114364-A1 SYNTHESIS OF PHENYL-SUBSTITUTED POLYFLUOROANTHENES AND THE USE THEREOF BASF AKTIENGESELLSCHAFT (DE) 2006-11-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10680182-B2 Fluoranthene compound, and organic electronic device comprising same AFF2, ESR1, AFF4 ALDH1A1 1216/4885CES2 1219/4885BCHE 1745/4885
US-20150236273-A1 FLUORANTHENE COMPOUND, AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME AFF2, ESR1, AFF4 ALDH1A1 1216/4885CES2 1219/4885BCHE 1745/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.