Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 4/20 | 0.52 |
| ▸ | MMP2 | P08253 | 4/20 | 0.52 |
| ▸ | MMP9 | P14780 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | P4HB | P07237 | 1/20 | 0.49 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | CDK4 | P11802 | 1/20 | 0.47 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.47 |
| ▸ | CCND1 | P24385 | 1/20 | 0.47 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | NOS2 | P35228 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7598085 | 0.95 | MMP1 (0.51) | MMP1MMP2MMP9KDM4EGLO1 | |
| SCHEMBL6381221 | 0.85 | KDM4E (0.62) | MMP1MMP2MMP9KDM4EMAOA | |
| SCHEMBL11126196 | 0.80 | MAPT (0.55) | MMP1MMP2MMP9MAOAMAOB | |
| SCHEMBL16414211 | 0.79 | MMP1 (0.51) | MMP1MMP2MMP9MAOAMAOB | |
| SCHEMBL16414210 | 0.79 | MMP1 (0.51) | MMP1MMP2MMP9MAOAMAOB | |
| SCHEMBL7585198 | 0.79 | HSD17B10 (0.62) | MMP1MMP2MMP9KDM4EGLO1 | |
| SCHEMBL30938425 | 0.79 | KDM4E (0.55) | KDM4EGLO1CCNB2CDK1CDK4 | |
| SCHEMBL7551989 | 0.79 | KDM4E (0.55) | KDM4EGLO1CCNB2CDK1CDK4 | |
| SCHEMBL31634782 | 0.79 | KDM4E (0.55) | KDM4EGLO1CCNB2CDK1CDK4 | |
| SCHEMBL442408 | 0.78 | NPSR1 (0.65) | MMP1MMP2MMP9KDM4EMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3060574-A1 | ALPHA BETA MODULATING PEPTIDES | Alzhyme Pty Ltd (AU) | 2016-08-31 | — | — | EP | disclosed |
| WO-2015058258-A1 | AΒ MODULATING PEPTIDES | ALZHYME PTY LTD (AU) | 2015-04-30 | — | — | WO | disclosed |
| CN-1279053-C | Modulators for beta-amyloid peptide aggregation comprising D-amino acids | PRAECIS PHARM INC (US) | 2006-10-11 | — | — | CN | disclosed |