Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 6/20 | 0.51 |
| ▸ | MMP2 | P08253 | 6/20 | 0.51 |
| ▸ | MMP9 | P14780 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16670788 | 0.95 | MMP1 (0.52) | MMP1MMP2MMP9KDM4EMAOA | |
| SCHEMBL11126196 | 0.85 | MAPT (0.55) | MMP1MMP2MMP9MAOAMAOB | |
| SCHEMBL6381221 | 0.84 | KDM4E (0.62) | MMP1MMP2MMP9KDM4EMAOA | |
| SCHEMBL7584015 | 0.79 | TYR (0.58) | MMP1MMP2MMP9KDM4EMAOA | |
| SCHEMBL28435739 | 0.78 | MAPT (0.59) | MMP1MMP2MMP9MAOAMAOB | |
| SCHEMBL9416654 | 0.78 | MAPT (0.59) | MMP1MMP2MMP9MAOAMAOB | |
| SCHEMBL27541702 | 0.78 | KMT2A (0.54) | MAOBALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL30938425 | 0.78 | KDM4E (0.55) | KDM4EALDH1A1CYP3A4MAPTTDP1 | |
| SCHEMBL7551989 | 0.78 | KDM4E (0.55) | KDM4EALDH1A1CYP3A4MAPTTDP1 | |
| SCHEMBL31634782 | 0.78 | KDM4E (0.55) | KDM4EALDH1A1CYP3A4MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263454-A2 | METHODS FOR ENHANCING THE BIOAVAILABILITY OF A DRUG | Praecis Pharmaceuticals Incorporated (US) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001058470-A2 | METHODS FOR ENHANCING THE BIOAVAILABILITY OF A DRUG | PRAECIS PHARMACEUTICALS INCORPORATED (US) | 2001-08-16 | — | — | WO | disclosed |