Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | TTR | P02766 | 2/20 | 0.62 |
| ▸ | APP | P05067 | 2/20 | 0.62 |
| ▸ | MMP1 | P03956 | 2/20 | 0.62 |
| ▸ | MMP2 | P08253 | 2/20 | 0.62 |
| ▸ | MMP9 | P14780 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.62 |
| ▸ | CA12 | O43570 | 1/20 | 0.62 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | CA3 | P07451 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6380450 | 0.84 | EGFR (0.61) | HSD17B10KDM4EMAPTTTRAPP | |
| SCHEMBL15082748 | 0.84 | EGFR (0.61) | HSD17B10KDM4EMAPTTTRAPP | |
| SCHEMBL31110546 | 0.84 | GLO1 (0.67) | KDM4EAPPCA12CA1CA2 | |
| SCHEMBL7581752 | 0.83 | GLO1 (0.69) | KDM4EMAPTAPPTDP1MEN1 | |
| SCHEMBL30497483 | 0.83 | GLO1 (0.87) | HSD17B10KDM4EMAPTAPPMMP9 | |
| SCHEMBL7585369 | 0.83 | GLO1 (0.87) | HSD17B10KDM4EMAPTAPPMMP9 | |
| SCHEMBL6535158 | 0.80 | TTR (0.66) | HSD17B10KDM4EMAPTTTRAPP | |
| SCHEMBL16670788 | 0.79 | MMP1 (0.52) | KDM4EMMP1MMP2MMP9AKR1B10 | |
| SCHEMBL7584015 | 0.78 | TYR (0.58) | KDM4EMAPTMMP1MMP2MMP9 | |
| SCHEMBL31452785 | 0.78 | MAPT (0.57) | HSD17B10KDM4EMAPTTTRAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4124724-A | Crystalline caffeic acid derivatives and compositions and method for treating snakebite | AGORO JOHN W | 1978-11-07 | — | — | US | claimed |
| CN-1279053-C | Modulators for beta-amyloid peptide aggregation comprising D-amino acids | PRAECIS PHARM INC (US) | 2006-10-11 | — | — | CN | disclosed |
| WO-2000052048-A9 | MODULATORS OF BETA-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS | PRAECIS PHARM INC (US) | 2002-04-11 | — | — | WO | disclosed |
| US-4124724-A | Crystalline caffeic acid derivatives and compositions and method for treating snakebite | AGORO JOHN W | 1978-11-07 | — | — | US | disclosed |