SCHEMBL166730

SCHEMBL166730

N#CCCc1ccccc1C(=S)S

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
FOLH1 Q04609 1/20 0.37
FFAR1 O14842 1/20 0.33
FFAR4 Q5NUL3 1/20 0.33
GAA P10253 1/20 0.31
EGFR P00533 1/20 0.31
TSHR P16473 1/20 0.31
CYP1A1 P04798 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP1B1 Q16678 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiobenzoic Acid SCHEMBL28014264 0.78 ALDH1A1 (0.35) MEN1KMT2AFOLH1FFAR1FFAR4
SCHEMBL9034382 0.78 FOLH1 (0.43) MEN1KMT2AFOLH1FFAR1FFAR4
SCHEMBL1890804 0.76 FOLH1 (0.59) FOLH1FFAR1FFAR4GAATSHR
SCHEMBL8764227 0.76 MEN1 (0.52) MEN1KMT2AFFAR1FFAR4EGFR
SCHEMBL28293863 0.76 FOLH1 (0.40) KMT2AFOLH1
SCHEMBL4347735 0.75 ALDH1A1 (0.42) MEN1KMT2AFOLH1FFAR1FFAR4
SCHEMBL1882898 0.75 ALDH1A1 (0.41) MEN1KMT2AFOLH1FFAR1FFAR4
SCHEMBL166497 0.74 ALDH1A1 (0.51) MEN1KMT2AFOLH1TSHR
SCHEMBL7085183 0.73 LIPG (0.44) FOLH1TSHR
SCHEMBL10919094 0.72 HPGD (0.43) MEN1KMT2AFOLH1GAATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2478021-B1 Nitrile rubbers and production of same in organic solvents LANXESS DEUTSCHLAND GMBH (DE) 2015-11-04 EP claimed
EP-2739661-A1 PROCESS FOR PRODUCING NITRILE RUBBERS IN ORGANIC SOLVENTS LANXESS Deutschland GmbH (DE) 2014-06-11 EP claimed
WO-2013017610-A1 PROCESS FOR PRODUCING NITRILE RUBBERS IN ORGANIC SOLVENTS LANXESS DEUTSCHLAND GMBH (DE) 2013-02-07 WO claimed
EP-2554558-A1 Method for producing nitrile rubbers in organic solvents Lanxess Deutschland GmbH (DE) 2013-02-06 EP claimed
EP-2478021-A1 NITRILE RUBBERS AND PRODUCTION THEREOF IN ORGANIC SOLVENTS Lanxess Deutschland GmbH (DE) 2012-07-25 EP claimed
EP-2423238-A1 Method for producing nitrile rubbers in organic solvents LANXESS Deutschland GmbH (DE) 2012-02-29 EP claimed
EP-2385074-A1 Nitrile rubbers and production of same in organic solvents LANXESS Deutschland GmbH (DE) 2011-11-09 EP claimed
US-8038675-B2 Apparatus for arrhythmia treatment based on spectral mapping during sinus rhythm ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. (US) 2011-10-18 US claimed
WO-2011032832-A1 NITRILE RUBBERS AND PRODUCTION THEREOF IN ORGANIC SOLVENTS LANXESS DEUTSCHLAND GMBH (DE) 2011-03-24 WO claimed
EP-2298824-A1 Nitrile rubbers and production of same in organic solvents LANXESS Deutschland GmbH (DE) 2011-03-23 EP claimed
EP-2478021-B1 Nitrile rubbers and production of same in organic solvents LANXESS DEUTSCHLAND GMBH (DE) 2015-11-04 EP disclosed
EP-2810956-A1 Nitrile rubbers coupled with bisdihydropyrazole groups, production and use of the same LANXESS Deutschland GmbH (DE) 2014-12-10 EP disclosed
EP-2810957-A1 Nitrile rubbers coupled with bisdihydropyrazole groups, production and use of the same LANXESS Deutschland GmbH (DE) 2014-12-10 EP disclosed
US-20140329982-A1 METHOD FOR PRODUCING PURIFIED NITRILE RUBBERS LANXESS DEUTSCHLAND GMBH (DE) 2014-11-06 US disclosed
EP-2798001-A1 METHOD FOR PRODUCING PURIFIED NITRILE RUBBERS LANXESS Deutschland GmbH (DE) 2014-11-05 EP disclosed
EP-2423234-A1 Rubber blends from different nitrile rubbers LANXESS Deutschland GmbH (DE) 2012-02-29 EP disclosed
EP-2385074-A1 Nitrile rubbers and production of same in organic solvents LANXESS Deutschland GmbH (DE) 2011-11-09 EP disclosed
US-8038675-B2 Apparatus for arrhythmia treatment based on spectral mapping during sinus rhythm ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC. (US) 2011-10-18 US disclosed
WO-2011032832-A1 NITRILE RUBBERS AND PRODUCTION THEREOF IN ORGANIC SOLVENTS LANXESS DEUTSCHLAND GMBH (DE) 2011-03-24 WO disclosed
EP-2298824-A1 Nitrile rubbers and production of same in organic solvents LANXESS Deutschland GmbH (DE) 2011-03-23 EP disclosed