Thiobenzoic Acid

Thiobenzoic Acid

SCHEMBL28014264

N#CCCc1ccccc1C(O)=S.OC(=S)c1ccccc1

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
KMT2A Q03164 3/20 0.34
MEN1 O00255 1/20 0.34
FOLH1 Q04609 1/20 0.34
FFAR1 O14842 1/20 0.34
FFAR4 Q5NUL3 1/20 0.34
ADRB2 P07550 1/20 0.33
NR1H2 P55055 1/20 0.32
NR1H3 Q13133 1/20 0.32
GAA P10253 1/20 0.32
CYP19A1 P11511 1/20 0.31
HTT P42858 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiobenzoic Acid SCHEMBL28348944 0.80 ALDH1A1 (0.50) ALDH1A1KMT2AMEN1ADRB2HTT
Thiobenzoic Acid SCHEMBL28627894 0.78 KMT2A (0.39) ALDH1A1KMT2AMEN1FOLH1ADRB2
SCHEMBL166730 0.78 MEN1 (0.37) KMT2AMEN1FOLH1FFAR1FFAR4
Thiobenzoic Acid SCHEMBL2457293 0.77 KMT2A (0.37) ALDH1A1KMT2AMEN1FOLH1ADRB2
SCHEMBL1890804 0.76 FOLH1 (0.59) ALDH1A1FOLH1FFAR1FFAR4GAA
Thiobenzoic Acid SCHEMBL5007779 0.75 LIPG (0.38) KMT2AHTTCYP3A4CYP2D6CYP2C9
Thiobenzoic Acid SCHEMBL28533220 0.74 LIPG (0.40) KMT2AHTTCYP3A4CYP2D6CYP2C9
SCHEMBL9034382 0.74 FOLH1 (0.43) ALDH1A1KMT2AMEN1FOLH1FFAR1
Thiobenzoic Acid SCHEMBL22325701 0.74 CLCN2 (0.40) ALDH1A1KMT2AGAAHTTCYP3A4
Thiobenzoic Acid SCHEMBL5082063 0.74 KMT2A (0.32) ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102498140-B Nitrile rubbers and production thereof in organic solvents LANXESS DEUTSCHLAND GMBH 2015-06-24 CN disclosed