Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ADH1B | P00325 | 1/20 | 0.33 |
| ▸ | ADH1C | P00326 | 1/20 | 0.33 |
| ▸ | ADH1A | P07327 | 1/20 | 0.33 |
| ▸ | ADH4 | P08319 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4744820 | 0.75 | SHBG (0.48) | ALDH1A1EPHX1CA12CA1SHBG | |
| SCHEMBL29673218 | 0.75 | SHBG (0.42) | ALDH1A1HSD17B10EPHX1CA12CA1 | |
| SCHEMBL28085019 | 0.75 | ALDH1A1 (0.38) | ALDH1A1HSD17B10EPHX1SHBGTP53 | |
| SCHEMBL28482536 | 0.74 | SHBG (0.37) | EPHX1CA12CA1SHBGTP53 | |
| SCHEMBL9963359 | 0.71 | TDP1 (0.41) | — | |
| SCHEMBL8861122 | 0.69 | EPHX1 (0.37) | ALDH1A1HSD17B10EPHX1CA12CA1 | |
| SCHEMBL20956954 | 0.69 | EPHX1 (0.48) | ALDH1A1HSD17B10EPHX1CA12CA1 | |
| SCHEMBL6557485 | 0.69 | CA12 (0.47) | ALDH1A1HSD17B10EPHX1CA12CA1 | |
| SCHEMBL15099936 | 0.69 | TP53 (0.44) | ALDH1A1HSD17B10EPHX1TP53KDM4E | |
| SCHEMBL16800874 | 0.69 | EPHX1 (0.42) | ALDH1A1HSD17B10EPHX1SHBGTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3066070-B1 | CATALYTIC HYDROGENATION FOR THE PREPARATION OF AMINES FROM AMIDE ACETALS, KETENE-N, O-ACETALS OR ESTERIMIDES | EVONIK DEGUSSA GMBH (DE) | 2019-07-17 | — | — | EP | disclosed |
| CN-105873897-B | For preparing the catalytic hydrogenation of amine from amide acetals, ketenes N, O- acetal or ester acid imide | 赢创德固赛有限公司 | 2018-06-15 | — | — | CN | disclosed |
| US-9890108-B2 | Catalytic hydrogenation for the preparation of amines from amide acetals, ketene N, O-acetals or ester imides | EVONIK DEGUSSA GMBH (DE) | 2018-02-13 | — | — | US | disclosed |
| US-20160264513-A1 | Catalytic Hydrogenation for the Preparation of Amines from Amide Acetals, Ketene N,O-Acetals or Ester Imides | EVONIK DEGUSSA GMBH (DE) | 2016-09-15 | — | — | US | disclosed |
| EP-3066070-A1 | CATALYTIC HYDROGENATION FOR THE PREPARATION OF AMINES FROM AMIDE ACETALS, KETENE N,O-ACETALS OR ESTER IMIDES | Evonik Degussa GmbH (DE) | 2016-09-14 | — | — | EP | disclosed |
| WO-2015067448-A1 | CATALYTIC HYDROGENATION FOR THE PREPARATION OF AMINES FROM AMIDE ACETALS, KETENE N,O-ACETALS OR ESTER IMIDES | EVONIK INDUSTRIES AG (DE) | 2015-05-14 | — | — | WO | disclosed |
| EP-2868652-A1 | Catalytic hydrogenation for the preparation of amines from amide acetals, ketene-N, O-acetals or esterimides | Evonik Industries AG (DE) | 2015-05-06 | — | — | EP | disclosed |
| US-20140107135-A1 | PYRIMIDINONE INHIBITORS OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 | AUSPEX PHARMACEUTICALS, INC. (US) | 2014-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160264513-A1 | Catalytic Hydrogenation for the Preparation of Amines from Amide Acetals, Ketene N,O-Acetals or Ester Imides | H1-0, H1-2, H1-10 | ALDH1A1 898/4885HSD17B10 295/4885EPHX1 1296/4885 |
| US-20140107135-A1 | PYRIMIDINONE INHIBITORS OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 | PLA2G1B, PLA2G4A, PLA2G4B | ALDH1A1 1423/4885HSD17B10 1164/4885EPHX1 523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.