Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29668340 | 1.00 | SMN1; SMN2 (0.51) | SMN1; SMN2NLRP3ALDH1A1HSD17B10PKM | |
| SCHEMBL27459157 | 0.86 | NLRP3 (0.53) | SMN1; SMN2NLRP3ALDH1A1HSD17B10PKM | |
| SCHEMBL11210879 | 0.85 | SMN1; SMN2 (0.45) | SMN1; SMN2NLRP3ALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL29591476 | 0.84 | EGFR (0.48) | SMN1; SMN2NLRP3ALDH1A1HSD17B10PKM | |
| SCHEMBL21437740 | 0.84 | EGFR (0.48) | SMN1; SMN2NLRP3ALDH1A1HSD17B10PKM | |
| SCHEMBL12345408 | 0.84 | EGFR (0.55) | SMN1; SMN2ALDH1A1PKMTP53MAPT | |
| SCHEMBL10015983 | 0.84 | NPC1 (0.45) | SMN1; SMN2ALDH1A1HSD17B10MAPTEGFR | |
| SCHEMBL11304499 | 0.83 | MAPT (0.43) | SMN1; SMN2NLRP3ALDH1A1HSD17B10PKM | |
| SCHEMBL10733546 | 0.83 | SMN1; SMN2 (0.43) | SMN1; SMN2NLRP3ALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL21437852 | 0.83 | NLRP3 (0.43) | SMN1; SMN2NLRP3ALDH1A1HSD17B10PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003915-A | Solid catalyst component, preparation method thereof, olefin polymerization catalyst and application | 中国石油化工股份有限公司 | 2023-11-07 | — | — | CN | disclosed |
| US-11708347-B2 | Substituted benzofuran, benzopyrrole, benzothiophene, and structurally related complement inhibitors | BIOCRYST PHARMACEUTICALS, INC. (US) | 2023-07-25 | — | — | US | disclosed |
| CN-111057168-B | Catalyst for olefin polymerization and preparation method and application thereof | 中国石油化工股份有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-112778442-A | Olefin polymerization catalyst solid component, preparation method thereof, olefin polymerization catalyst and application | 中国石油化工股份有限公司 | 2021-05-11 | — | — | CN | disclosed |
| CN-112759683-A | Olefin polymerization catalyst and application | 中国石油化工股份有限公司 | 2021-05-07 | — | — | CN | disclosed |
| CN-111057168-A | Catalyst for olefin polymerization and preparation method and application thereof | 中国石油化工股份有限公司 | 2020-04-24 | — | — | CN | disclosed |
| EP-2869389-B1 | NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS ELECTROLYTIC SOLUTION CELL USING SAME | MITSUBISHI CHEM CORP (JP) | 2019-11-13 | — | — | EP | disclosed |
| US-10320030-B2 | Nonaqueous electrolyte solution and nonaqueous electrolyte battery employing the same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2019-06-11 | — | — | US | disclosed |
| CN-103772536-B | A kind of catalytic component for vinyl polymerization or combined polymerization and catalyst thereof | SINOPEC CORP. (CN) | 2016-05-25 | — | — | CN | disclosed |
| US-20150140448-A1 | NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY EMPLOYING THE SAME | MITSUBISHI CHEMICAL CORPORATION (JP) | 2015-05-21 | — | — | US | disclosed |
| EP-2869389-A1 | NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS ELECTROLYTIC SOLUTION CELL USING SAME | Mitsubishi Chemical Corporation (JP) | 2015-05-06 | — | — | EP | disclosed |
| CN-103772536-A | Catalyst component for polymerization or copolymerization of ethylene and catalyst thereof | CHINA PETROLEUM & CHEMICAL | 2014-05-07 | — | — | CN | disclosed |
| US-20140107135-A1 | PYRIMIDINONE INHIBITORS OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 | AUSPEX PHARMACEUTICALS, INC. (US) | 2014-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140107135-A1 | PYRIMIDINONE INHIBITORS OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 | PLA2G1B, PLA2G4A, PLA2G4B | SMN1; SMN2 4141/4885NLRP3 2041/4885ALDH1A1 1423/4885 |
| US-11708347-B2 | Substituted benzofuran, benzopyrrole, benzothiophene, and structurally related complement inhibitors | C9, C5, C1QBP | SMN1; SMN2 2080/4885NLRP3 24/4885ALDH1A1 1047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.