Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CCR8 | P51685 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12438413 | 0.87 | MAPT (0.48) | MAPTPKMSLC6A3TSHRALDH1A1 | |
| SCHEMBL18828251 | 0.82 | TRPM8 (0.50) | MAPTPKMALDH1A1 | |
| SCHEMBL14189731 | 0.82 | TRPM8 (0.50) | MAPTPKMALDH1A1 | |
| SCHEMBL20073034 | 0.82 | TRPM8 (0.50) | MAPTPKMALDH1A1 | |
| SCHEMBL233023 | 0.82 | TRPM8 (0.50) | MAPTPKMALDH1A1 | |
| SCHEMBL14189736 | 0.82 | TRPM8 (0.50) | MAPTPKMALDH1A1 | |
| SCHEMBL3172897 | 0.80 | ELANE (0.53) | GAASLC6A3ALDH1A1NPC1RAB9A | |
| SCHEMBL17852174 | 0.79 | TRPM8 (0.46) | MAPTPKM | |
| SCHEMBL11582365 | 0.77 | ALDH1A1 (0.52) | MAPTPKMTSHRALDH1A1RAB9A | |
| SCHEMBL14465136 | 0.77 | TRPM8 (0.47) | MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307476-A1 | ASYMMETRIC CYCLIC DIESTER COMPOUNDS | FERRO CORPORATION (US) | 2011-04-13 | — | — | EP | disclosed |
| WO-2009152068-A1 | ASYMMETRIC CYCLIC DIESTER COMPOUNDS | FERRO CORPORATION (US) | 2009-12-17 | — | — | WO | disclosed |