Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ASPH | Q12797 | 1/20 | 0.38 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 4/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22502922 | 0.75 | CCR1 (0.34) | KDM4ERAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL30478284 | 0.73 | DPP4 (0.35) | KDM4ELMNA | |
| SCHEMBL22502905 | 0.73 | KDM4E (0.30) | KDM4ELMNA | |
| SCHEMBL25292129 | 0.73 | DPP4 (0.35) | KDM4ELMNA | |
| SCHEMBL18248861 | 0.72 | KDM5A (0.35) | DHODHKDM4EASPHKDM8KDM4A | |
| SCHEMBL5057148 | 0.71 | FABP4 (0.49) | KDM4EASPHKDM8LMNAKDM5A | |
| SCHEMBL3669343 | 0.69 | ALDH1A1 (0.40) | KDM4EKDM4ARAB9AEGLN1HIF1AN | |
| SCHEMBL3669340 | 0.68 | KDM5B (0.37) | KDM4EASPHKDM8KDM4ARAB9A | |
| SCHEMBL1665551 | 0.67 | KDM5B (0.47) | KDM4AKDM5AKDM5BKDM4C | |
| SCHEMBL11630217 | 0.66 | KDM4E (0.36) | KDM4EASPHKDM8KDM4ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2308867-A2 | 2-oxo-1-pyrrolidine deriatives, processes for preparing them and their uses | UCB Pharma S.A. (BE) | 2011-04-13 | — | — | EP | disclosed |