Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16674862 | 0.80 | TSHR (0.42) | MAPTALDH1A1HTTTSHRLMNA | |
| SCHEMBL9852541 | 0.74 | LMNA (0.61) | MAPTKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL11684908 | 0.72 | CA1 (0.48) | MAPTKDM4EALDH1A1GAAHSD17B10 | |
| SCHEMBL3403381 | 0.69 | CA12 (0.46) | KDM4EALDH1A1GAATSHRHPGD | |
| SCHEMBL6243144 | 0.68 | KDM4E (0.72) | MAPTKDM4EALDH1A1HSD17B10HTT | |
| SCHEMBL11168943 | 0.68 | LMNA (0.49) | MAPTKDM4EALDH1A1GAAHSD17B10 | |
| SCHEMBL28367227 | 0.67 | CA12 (0.40) | MAPTKDM4EALDH1A1GAAHSD17B10 | |
| SCHEMBL28774875 | 0.67 | LMNA (0.43) | MAPTKDM4EALDH1A1HSD17B10HTT | |
| SCHEMBL11713096 | 0.67 | TSHR (0.41) | MAPTKDM4EALDH1A1GAAHSD17B10 | |
| SCHEMBL6243177 | 0.66 | NPC1 (0.72) | MAPTKDM4EALDH1A1HSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9328198-B2 | Composition for forming resist underlayer | AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (LU) | 2016-05-03 | — | — | US | disclosed |
| US-20150118624-A1 | COMPOSITION FOR FORMING RESIST UNDERLAYER | AZ ELECTRONIC MATERIALS S.À R.L. (LU) | 2015-04-30 | — | — | US | disclosed |