SCHEMBL28367227

SCHEMBL28367227

COC(=O)c1c(I)c(N)c(I)c(C(=O)OC)c1I

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
CA14 Q9ULX7 1/20 0.40
KDM4E B2RXH2 7/20 0.38
ALDH1A1 P00352 7/20 0.38
KMT2A Q03164 4/20 0.38
HSD17B10 Q99714 4/20 0.38
HPGD P15428 4/20 0.38
MEN1 O00255 3/20 0.38
GAA P10253 2/20 0.37
MAPT P10636 2/20 0.37
GLA P06280 1/20 0.37
ALOX15 P16050 1/20 0.37
ATM Q13315 1/20 0.37
CFTR P13569 2/20 0.36
NPSR1 Q6W5P4 1/20 0.36
POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14958982 0.92 ALDH1A1 (0.37) CA12CA1CA2CA7CA9
SCHEMBL29557419 0.92 CA12 (0.35) CA12CA1CA2CA7CA9
SCHEMBL28367230 0.92 CA12 (0.35) CA12CA1CA2CA7CA9
SCHEMBL29557234 0.90 CA12 (0.34) CA12CA1CA2CA7CA9
SCHEMBL11684908 0.83 CA1 (0.48) CA12CA1CA2CA7CA9
SCHEMBL15358293 0.83 CA12 (0.48) CA12CA1CA2CA7CA9
SCHEMBL11168943 0.82 LMNA (0.49) CA12CA1CA2CA7CA9
SCHEMBL3403381 0.79 CA12 (0.46) CA12CA1CA2CA7CA9
SCHEMBL9387753 0.78 CFTR (0.41) CA12CA1CA2CA7CA9
SCHEMBL11549333 0.77 KDM4E (0.31) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4687672-A1 RADIOPAQUE POLYSACCHARIDE HYDROGELS AND METHODS OF MAKING THE SAME Boston Scientific Scimed Inc. (US) 2026-02-11 EP disclosed
US-20250249130-A1 RADIOPAQUE POLYPEPTIDES FOR INJECTABLE COMPOSITIONS BOSTON SCIENTIFIC SCIMED, INC. (US) 2025-08-07 US disclosed
US-20250059237-A1 METHODS OF FORMING RADIOPAQUE PEPTIDES AND MEDICAL HYDROGELS FORMED THEREFROM BOSTON SCIENTIFIC SCIMED, INC. (US) 2025-02-20 US disclosed
WO-2025038709-A1 METHODS OF FORMING RADIOPAQUE PEPTIDES AND MEDICAL HYDROGELS FORMED THEREFROM BOSTON SCIENTIFIC SCIMED, INC. (US) 2025-02-20 WO disclosed
WO-2024211688-A1 RADIOPAQUE POLYSACCHARIDE HYDROGELS AND METHODS OF MAKING THE SAME BOSTON SCIENTIFIC SCIMED, INC. (US) 2024-10-10 WO disclosed
US-20240335568-A1 RADIOPAQUE POLYSACCHARIDE HYDROGELS AND METHODS OF MAKING THE SAME BOSTON SCIENTIFIC SCIMED, INC. (US) 2024-10-10 US disclosed
CN-110903275-A Process for producing iobitridol, intermediate therefor, and process for producing the same 苏州科伦药物研究有限公司 2020-03-24 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240335568-A1 RADIOPAQUE POLYSACCHARIDE HYDROGELS AND METHODS OF MAKING THE SAME CD44, ALG1, CA13 CA12 13/4885CA1 73/4885CA2 544/4885
US-20250059237-A1 METHODS OF FORMING RADIOPAQUE PEPTIDES AND MEDICAL HYDROGELS FORMED THEREFROM HDGF, IAPP, QRFPR CA12 1869/4885CA1 2660/4885CA2 4132/4885
US-20250249130-A1 RADIOPAQUE POLYPEPTIDES FOR INJECTABLE COMPOSITIONS IAPP, IGFBP6, NPPA CA12 520/4885CA1 1262/4885CA2 3237/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.