Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | THRB | P10828 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | PTPRA | P18433 | 1/20 | 0.53 |
| ▸ | PTPRB | P23467 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.52 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.49 |
| ▸ | MPL | P40238 | 5/20 | 0.48 |
| ▸ | CTRC | Q99895 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29374890 | 0.94 | MAPK1 (0.80) | MAPK1ALDH1A1KMT2AMEN1THRB | |
| SCHEMBL344614 | 0.94 | MAPK1 (0.80) | MAPK1ALDH1A1KMT2AMEN1THRB | |
| SCHEMBL112109 | 0.94 | MAPK1 (0.80) | MAPK1ALDH1A1KMT2AMEN1THRB | |
| SCHEMBL29694156 | 0.94 | MAPK1 (0.80) | MAPK1ALDH1A1KMT2AMEN1THRB | |
| SCHEMBL185436 | 0.94 | MAPK1 (0.80) | MAPK1ALDH1A1KMT2AMEN1THRB | |
| SCHEMBL29378602 | 0.93 | MAPK1 (0.78) | MAPK1ALDH1A1KMT2AMEN1THRB | |
| SCHEMBL30509839 | 0.93 | MAPK1 (0.78) | MAPK1ALDH1A1KMT2AMEN1THRB | |
| SCHEMBL3199291 | 0.93 | MAPK1 (0.78) | MAPK1ALDH1A1KMT2AMEN1THRB | |
| SCHEMBL185435 | 0.93 | MAPK1 (0.78) | MAPK1ALDH1A1KMT2AMEN1THRB | |
| SCHEMBL19697192 | 0.90 | MAPK1 (0.70) | MAPK1ALDH1A1KMT2AMEN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150113742-A1 | ANIONIC DYE OR BRIGHTENER BEARING AN AMMONIUM OR PHOSPHONIUM COUNTERION, DYE COMPOSITION COMPRISING THEM AND PROCESS FOR DYEING KERATIN FIBRES USING THESE DYES | L'OREAL (FR) | 2015-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150113742-A1 | ANIONIC DYE OR BRIGHTENER BEARING AN AMMONIUM OR PHOSPHONIUM COUNTERION, DYE COMPOSITION COMPRISING THEM AND PROCESS FOR DYEING KERATIN FIBRES USING THESE DYES | KRT18, IK, COL14A1 | MAPK1 2118/4885ALDH1A1 1961/4885KMT2A 2612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.