SCHEMBL112109

SCHEMBL112109

O=S(=O)(O)c1cc(S(=O)(=O)O)c2c(/N=N/c3ccc(S(=O)(=O)O)c4ccccc34)c(O)ccc2c1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.80
ALDH1A1 P00352 2/20 0.80
KMT2A Q03164 4/20 0.61
MEN1 O00255 3/20 0.61
TDP1 Q9NUW8 2/20 0.61
THRB P10828 2/20 0.61
CYP1A2 P05177 5/20 0.57
CYP2C9 P11712 2/20 0.57
HIF1A Q16665 2/20 0.57
TSHR P16473 1/20 0.57
PTPRA P18433 1/20 0.57
PTPRB P23467 1/20 0.57
CYP2C19 P33261 1/20 0.57
RAPGEF4 Q8WZA2 1/20 0.57
HSD17B10 Q99714 1/20 0.57
CTRB1 P17538 1/20 0.56
PRMT1 Q99873 1/20 0.55
DNASE1L3 Q13609 1/20 0.53
MPL P40238 5/20 0.52
CTRC Q99895 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29374890 1.00 MAPK1 (0.80) MAPK1ALDH1A1KMT2AMEN1TDP1
SCHEMBL29694156 1.00 MAPK1 (0.80) MAPK1ALDH1A1KMT2AMEN1TDP1
SCHEMBL344614 1.00 MAPK1 (0.80) MAPK1ALDH1A1KMT2AMEN1TDP1
SCHEMBL185436 1.00 MAPK1 (0.80) MAPK1ALDH1A1KMT2AMEN1TDP1
SCHEMBL29378602 0.99 MAPK1 (0.78) MAPK1ALDH1A1KMT2AMEN1TDP1
SCHEMBL30509839 0.99 MAPK1 (0.78) MAPK1ALDH1A1KMT2AMEN1TDP1
SCHEMBL185435 0.99 MAPK1 (0.78) MAPK1ALDH1A1KMT2AMEN1TDP1
SCHEMBL3199291 0.99 MAPK1 (0.78) MAPK1ALDH1A1KMT2AMEN1TDP1
SCHEMBL15242111 0.94 MAPK1 (0.74) MAPK1ALDH1A1KMT2AMEN1TDP1
SCHEMBL5159519 0.94 MAPK1 (0.74) MAPK1ALDH1A1KMT2AMEN1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 354 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12624132-B2 Liquid polymerizable allylic compositions comprising lake pigments ESSILOR INTERNATIONAL (FR) 2026-05-12 US claimed
US-20240400725-A1 LIQUID POLYMERIZABLE ALLYLIC COMPOSITIONS COMPRISING LAKE PIGMENTS ESSILOR INTERNATIONAL (FR) 2024-12-05 US claimed
EP-3727287-B1 HAIR DYEING PROCESS COMPRISING A STEP OF DYEING WITH HENNA AND/OR INDIGO AND A TREATMENT STEP COMPRISING THE APPLICATION OF A COMPOSITION COMPRISING A BUFFER SYSTEM OREAL (FR) 2024-12-04 EP claimed
EP-3366750-B1 STABILIZER AND STABILIZATION METHOD FUJIFILM WAKO PURE CHEMICAL CORP (JP) 2021-07-21 EP claimed
EP-2543706-B1 METHOD FOR STABILIZING OF COLOR DEVELOPER AND USE THEREOF ARKRAY INC (JP) 2021-05-26 EP claimed
US-10961185-B2 Stabilizer and stabilization method FUJIFILM WAKO PURE CHEMICAL CHEMICAL CORPORATION (JP) 2021-03-30 US claimed
CN-108138047-B Stabilizer and stabilization method 富士胶片和光纯药株式会社 2021-02-09 CN claimed
EP-3727287-A1 HAIR DYEING PROCESS COMPRISING A STEP OF DYEING WITH HENNA AND/OR INDIGO AND A TREATMENT STEP COMPRISING THE APPLICATION OF A COMPOSITION COMPRISING A BUFFER SYSTEM L'OREAL (FR) 2020-10-28 EP claimed
WO-2019216829-A1 APPLICATION OF A FOOD AZO DYE, BRILLIANT BLACK BN, ON INHIBITION OF INFECTIVITY OF HUMAN ENTEROVIRUSES CAUSING HAND FOOT AND MOUTH DISEASES TEMASEK LIFE SCIENCES LABORATORY LIMITED (SG) 2019-11-14 WO claimed
US-20180290969-A1 STABILIZER AND STABILIZATION METHOD FUJIFILM WAKO PURE CHEMICAL CHEMICAL CORPORATION (JP) 2018-10-11 US claimed
WO-2018115450-A1 PROCESS FOR DIRECT DYEING OF KERATIN FIBRES COMPRISING THE APPLICATION OF TWO PARTICULAR COMPOSITIONS L'OREAL (FR) 2018-06-28 WO claimed
WO-2018115451-A1 COSMETIC COMPOSITION FOR DIRECT DYEING COMPRISING AN AQUEOUS PHASE AND A FATTY PHASE THAT ARE VISUALLY DISTINCT FROM EACH OTHER L'OREAL (FR) 2018-06-28 WO claimed
EP-3001190-A1 METHOD FOR DETECTING PHENOTHIAZINE-DERIVATIVE COLOR AND COLOR-DEVELOPER REAGENT USED THEREIN ARKRAY, Inc. (JP) 2016-03-30 EP claimed
EP-2543706-A2 Stabilizer of color former and use thereof ARKRAY, Inc. (JP) 2013-01-09 EP claimed
US-8273577-B2 Method for detecting phenothiazine-derivative color and color-developer reagent used therein ARKRAY, INC. (JP) 2012-09-25 US claimed
US-20110015391-A1 STABILIZER OF COLOR FORMER AND USE THEREOF ARKRAY, INC. (JP) 2011-01-20 US claimed
EP-2270105-A1 STABILIZER FOR COLOR DEVELOPER AND USE THEREOF ARKRAY, Inc. (JP) 2011-01-05 EP claimed
WO-2010055371-A1 MEDICAMENT FOR INHIBITING THE SYNTHESIS OF LEUKOTRIENES PICHLER CHRISTIAN (AT) 2010-05-20 WO claimed
US-20100112622-A1 METHOD FOR DETECTING PHENOTHIAZINE-DERIVATIVE COLOR AND COLOR-DEVELOPER REAGENT USED THEREIN ARKRAY, INC. (JP) 2010-05-06 US claimed
EP-2108952-A1 METHOD FOR DETECTION OF PHENOTHIAZINE DERIVATIVE DYE, AND COLOR-DEVELOPER REAGENT FOR USE IN THE METHOD Arkray, Inc. (JP) 2009-10-14 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624132-B2 Liquid polymerizable allylic compositions comprising lake pigments AP3M1, SCO2, MB MAPK1 1893/4885ALDH1A1 1704/4885KMT2A 2456/4885
US-20180290969-A1 STABILIZER AND STABILIZATION METHOD H1-0, H1-2, H1-4 MAPK1 778/4885ALDH1A1 993/4885KMT2A 144/4885
US-20100112622-A1 METHOD FOR DETECTING PHENOTHIAZINE-DERIVATIVE COLOR AND COLOR-DEVELOPER REAGENT USED THEREIN TH, TYR, HPD MAPK1 635/4885ALDH1A1 570/4885KMT2A 2700/4885
US-20110015391-A1 STABILIZER OF COLOR FORMER AND USE THEREOF TYR, CRYZ, MITF MAPK1 1280/4885ALDH1A1 223/4885KMT2A 774/4885
US-10961185-B2 Stabilizer and stabilization method H1-0, H1-2, H1-4 MAPK1 778/4885ALDH1A1 993/4885KMT2A 144/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.