SCHEMBL185435

SCHEMBL185435

O=S(=O)(O)c1cc(S(=O)(=O)O)c2c(/N=N/c3ccc(S(=O)(=O)O)c4ccccc34)c(O)ccc2c1.[NaH].[NaH].[NaH]

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.78
ALDH1A1 P00352 2/20 0.78
KMT2A Q03164 4/20 0.60
MEN1 O00255 3/20 0.60
TDP1 Q9NUW8 2/20 0.60
THRB P10828 2/20 0.60
CYP1A2 P05177 5/20 0.56
CYP2C9 P11712 2/20 0.56
HIF1A Q16665 2/20 0.56
TSHR P16473 1/20 0.56
PTPRA P18433 1/20 0.56
PTPRB P23467 1/20 0.56
CYP2C19 P33261 1/20 0.56
RAPGEF4 Q8WZA2 1/20 0.56
HSD17B10 Q99714 1/20 0.56
CTRB1 P17538 1/20 0.55
PRMT1 Q99873 1/20 0.54
DNASE1L3 Q13609 1/20 0.53
MPL P40238 5/20 0.51
CTRC Q99895 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3199291 1.00 MAPK1 (0.78) MAPK1ALDH1A1KMT2AMEN1TDP1
SCHEMBL29374890 0.99 MAPK1 (0.80) MAPK1ALDH1A1KMT2AMEN1TDP1
SCHEMBL29694156 0.99 MAPK1 (0.80) MAPK1ALDH1A1KMT2AMEN1TDP1
SCHEMBL185436 0.99 MAPK1 (0.80) MAPK1ALDH1A1KMT2AMEN1TDP1
SCHEMBL344614 0.99 MAPK1 (0.80) MAPK1ALDH1A1KMT2AMEN1TDP1
SCHEMBL112109 0.99 MAPK1 (0.80) MAPK1ALDH1A1KMT2AMEN1TDP1
SCHEMBL30509839 0.98 MAPK1 (0.78) MAPK1ALDH1A1KMT2AMEN1TDP1
SCHEMBL29378602 0.98 MAPK1 (0.78) MAPK1ALDH1A1KMT2AMEN1TDP1
SCHEMBL15242111 0.93 MAPK1 (0.74) MAPK1ALDH1A1KMT2AMEN1TDP1
SCHEMBL16675035 0.93 MAPK1 (0.70) MAPK1ALDH1A1KMT2AMEN1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112384225-A Application of edible azo dye brilliant black BN in inhibiting infectivity of human enteroviruses causing hand-foot-and-mouth disease 淡马锡生命科学实验室有限公司 2021-02-19 CN claimed
EP-2930126-B1 Fashionable aerosol dye HENKEL AG & CO KGAA (DE) 2019-10-09 EP claimed
US-7241318-B2 Hair dye CREATE CO. (JP) 2007-07-10 US claimed
US-20040111810-A1 Hair dye CREATE CO. (JP) 2004-06-17 US claimed
CN-112384225-B Application of edible azo dye brilliant black BN in inhibiting infectivity of human enteroviruses causing hand-foot-mouth disease 淡马锡生命科学实验室有限公司 2024-06-14 CN disclosed
CN-115315230-A Method for manufacturing glazed dental prosthesis 士卓曼研究院股份公司 2022-11-08 CN disclosed
CN-112384225-A Application of edible azo dye brilliant black BN in inhibiting infectivity of human enteroviruses causing hand-foot-and-mouth disease 淡马锡生命科学实验室有限公司 2021-02-19 CN disclosed
US-10259946-B1 Sealing agents, methods of making and uses thereof James Hardie Technology Limited (IE) 2019-04-16 US disclosed
US-10179093-B2 Compositions and methods for coloring keratinic fibers HENKEL AG & CO. KGAA (DE) 2019-01-15 US disclosed
US-20170312188-A1 COMPOSITIONS AND METHODS FOR COLORING KERATINIC FIBERS HENKEL AG & CO. KGAA (DE) 2017-11-02 US disclosed
US-9173829-B2 Compositions for dyeing keratin fibers HENKEL AG & CO. KGAA (DE) 2015-11-03 US disclosed
US-9161898-B2 Compositions for colouring keratin fibres HENKEL AG & CO. KGAA (DE) 2015-10-20 US disclosed
EP-1350512-A1 Combinations of epinastine, belladonna and pseudoephedrine as new pharmaceutical formulations BOEHRINGER INGELHEIM INTERNATIONAL GmbH (DE) 2003-10-08 EP disclosed
US-20030163877-A1 Colouring composition UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2003-09-04 US disclosed
EP-1326586-A1 NEW PHARMACEUTICAL COMPOSITIONS CONTAINING EPINASTINE AND PSEUDOEPHEDRINE BOEHRINGER INGELHEIM INTERNATIONAL GmbH (DE) 2003-07-16 EP disclosed
EP-1317917-A1 Hair colouring composition comprising clay UNILEVER PLC (GB) 2003-06-11 EP disclosed
US-20020094345-A1 Pharmaceutical compositions containing epinastine and pseudoephedrine BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2002-07-18 US disclosed
WO-2002028373-A1 NEW PHARMACEUTICAL COMPOSITIONS CONTAINING EPINASTINE AND PSEUDOEPHEDRINE BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2002-04-11 WO disclosed
US-6171347-B1 REMOVAL OF HAIR COLOR TO BE WORN FOR ONLY A SHORT PERIOD OF TIME UNDER MILD, GENTLE CONDITIONS BY USING A COMBINATION OF A SUITABLE REDUCTONE, SUCH AS ASCORBIC ACID, AND/OR A THIOL AND/OR A SULFITE WELLA AKTIENGESELLSCHAFT (DE) 2001-01-09 US disclosed
US-4649219-A CROSSLINKERS, ADHESIVES, PAINTS MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1987-03-10 US disclosed