Sugi Predict

Sugi Predict / Compounds / SCHEMBL3199291

SCHEMBL3199291

SCHEMBL3199291

O=S(=O)(O)c1cc(S(=O)(=O)O)c2c(N=Nc3ccc(S(=O)(=O)O)c4ccccc34)c(O)ccc2c1.[NaH].[NaH].[NaH]

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 3/20 0.78
▸ ALDH1A1 P00352 2/20 0.78
▸ KMT2A Q03164 4/20 0.60
▸ MEN1 O00255 3/20 0.60
▸ TDP1 Q9NUW8 2/20 0.60
▸ THRB P10828 2/20 0.60
▸ CYP1A2 P05177 5/20 0.56
▸ CYP2C9 P11712 2/20 0.56
▸ HIF1A Q16665 2/20 0.56
▸ TSHR P16473 1/20 0.56
▸ PTPRA P18433 1/20 0.56
▸ PTPRB P23467 1/20 0.56
▸ CYP2C19 P33261 1/20 0.56
▸ RAPGEF4 Q8WZA2 1/20 0.56
▸ HSD17B10 Q99714 1/20 0.56
▸ CTRB1 P17538 1/20 0.55
▸ PRMT1 Q99873 1/20 0.54
▸ DNASE1L3 Q13609 1/20 0.53
▸ MPL P40238 5/20 0.51
▸ CTRC Q99895 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL185435 1.00 MAPK1 (0.78) MAPK1ALDH1A1KMT2AMEN1TDP1
SCHEMBL29374890 0.99 MAPK1 (0.80) MAPK1ALDH1A1KMT2AMEN1TDP1
SCHEMBL29694156 0.99 MAPK1 (0.80) MAPK1ALDH1A1KMT2AMEN1TDP1
SCHEMBL185436 0.99 MAPK1 (0.80) MAPK1ALDH1A1KMT2AMEN1TDP1
SCHEMBL344614 0.99 MAPK1 (0.80) MAPK1ALDH1A1KMT2AMEN1TDP1
SCHEMBL112109 0.99 MAPK1 (0.80) MAPK1ALDH1A1KMT2AMEN1TDP1
SCHEMBL30509839 0.98 MAPK1 (0.78) MAPK1ALDH1A1KMT2AMEN1TDP1
SCHEMBL29378602 0.98 MAPK1 (0.78) MAPK1ALDH1A1KMT2AMEN1TDP1
SCHEMBL15242111 0.93 MAPK1 (0.74) MAPK1ALDH1A1KMT2AMEN1TDP1
SCHEMBL16675035 0.93 MAPK1 (0.70) MAPK1ALDH1A1KMT2AMEN1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115315230-B Method for producing glazed dental prostheses 士卓曼研究院股份公司 2024-05-14 — — CN disclosed
US-10259946-B1 Sealing agents, methods of making and uses thereof James Hardie Technology Limited (IE) 2019-04-16 — — US disclosed
US-7670391-B2 Dye-containing pellets for coloring keratin fibers WELLA AG (DE) 2010-03-02 — — US disclosed
US-20090056039-A1 DYE-CONTAINING PELLETS FOR COLORING KERATIN FIBERS HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) 2009-03-05 — — US disclosed
US-7462204-B2 Cationic diaminopyrazoles, a process for producing them and colorants containing these compounds WELLA AG (DE) 2008-12-09 — — US disclosed
US-7458992-B2 Dye-containing pellets for dyeing keratin fibres WELLA AG (DE) 2008-12-02 — — US disclosed
US-7361198-B2 M-diaminobenzenes, their acid adducts and the use thereof in colorants WELLA AG (DE) 2008-04-22 — — US disclosed
US-7320711-B2 Dyestuff for keratin fibers WELLA AG (DE) 2008-01-22 — — US disclosed
US-20070199159-A1 Dye-containing pellets and their use PROCTER & GAMBLE COMPANY, THE 2007-08-30 — — US disclosed
EP-1820487-A1 Dye-containing pellets and their use Wella Aktiengesellschaft (DE) 2007-08-22 — — EP disclosed
US-20060183781-A1 Novel thiazolylmethyl pyrazoles, method for the production thereof, and use thereof in dyes for keratin fibers WELLA AG (DE) 2006-08-17 — — US disclosed
US-20060162097-A1 Dye-containing pellets for dyeing keratin fibres HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) 2006-07-27 — — US disclosed
US-20060121070-A1 Dyestuff for keratin fibers HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2006-06-08 — — US disclosed
US-7018426-B2 Oxidation dye WELLA AG (DE) 2006-03-28 — — US disclosed
US-20060047172-A1 M-diaminobenzenes, their acid adducts and the use thereof in colorants Wella GmbH (DE) 2006-03-02 — — US disclosed
US-20040098815-A1 Coluoring agent for keratin fibres HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2004-05-27 — — US disclosed
US-20030159222-A1 Oxidation dye HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2003-08-28 — — US disclosed
US-20020189031-A1 Use of salts for improving the absorption qualities of anionic direct dyes WELLA AKTIENGESELLSCHAFT (DE) 2002-12-19 — — US disclosed
US-4649219-A CROSSLINKERS, ADHESIVES, PAINTS MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1987-03-10 — — US disclosed
EP-0155177-A2 Unsaturated cyclic amido-substituted ether compounds and preparation process thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1985-09-18 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030159222-A1 Oxidation dye KRT18, NOX4, VIM MAPK1 859/4885ALDH1A1 55/4885KMT2A 2161/4885
US-20060047172-A1 M-diaminobenzenes, their acid adducts and the use thereof in colorants DDT, NQO1, MDH2 MAPK1 1071/4885ALDH1A1 25/4885KMT2A 807/4885
US-20060183781-A1 Novel thiazolylmethyl pyrazoles, method for the production thereof, and use thereof in dyes for keratin fibers KRT18, CBR3, CDC73 MAPK1 605/4885ALDH1A1 118/4885KMT2A 3398/4885
US-20040098815-A1 Coluoring agent for keratin fibres KRT18, DSG1, KIF5B MAPK1 1210/4885ALDH1A1 307/4885KMT2A 2888/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.