SCHEMBL16675190

SCHEMBL16675190

COCC(=O)Oc1ccc(C(=O)Nc2cc(NC(=O)c3ccc(OC(=O)COC)cc3)nc(NC(=O)c3ccc(OC(=O)COC)cc3)n2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.51
MAPT P10636 4/20 0.51
MEN1 O00255 2/20 0.51
KDM4E B2RXH2 1/20 0.51
RECQL P46063 1/20 0.51
NPC1 O15118 10/20 0.47
RAB9A P51151 10/20 0.47
SMN1; SMN2 Q16637 8/20 0.47
TP53 P04637 4/20 0.47
NFKB1 P19838 1/20 0.47
NFKB2 Q00653 1/20 0.47
RELA Q04206 1/20 0.47
CHRNB2 P17787 1/20 0.45
CHRNB4 P30926 1/20 0.45
CHRNA3 P32297 1/20 0.45
CHRNA4 P43681 1/20 0.45
ADORA3 P0DMS8 1/20 0.44
PKM P14618 2/20 0.43
CA2 P00918 1/20 0.42
F2 P00734 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16675184 0.87 KMT2A (0.53) KMT2AMAPTMEN1KDM4ERECQL
SCHEMBL16675196 0.84 MEN1 (0.56) KMT2AMAPTMEN1KDM4ERECQL
SCHEMBL16675194 0.82 RAB9A (0.63) KMT2AMAPTMEN1KDM4ERECQL
SCHEMBL16675189 0.82 KMT2A (0.73) KMT2AMAPTMEN1KDM4ERECQL
SCHEMBL16675198 0.79 ELANE (0.53) KMT2AMAPTMEN1KDM4ERECQL
SCHEMBL15308163 0.77 MEN1 (0.66) KMT2AMAPTMEN1KDM4ERECQL
SCHEMBL16675192 0.77 ADORA3 (0.50) KMT2AMAPTMEN1KDM4ERECQL
SCHEMBL16677987 0.76 NPC1 (0.55) KMT2AMAPTMEN1KDM4ERECQL
SCHEMBL16677952 0.76 NPC1 (0.55) KMT2AMAPTMEN1KDM4ERECQL
SCHEMBL16675207 0.76 RAB9A (0.55) KMT2AMAPTMEN1KDM4ERECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150114257-A1 METHOD OF PREPARING RETARDATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY Konica Minolta, Inc. (JP) 2015-04-30 US disclosed
US-20150114257-A1 METHOD OF PREPARING RETARDATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY Konica Minolta, Inc. (JP) 2015-04-30 US disclosed