SCHEMBL16675192

SCHEMBL16675192

O=C(Oc1ccccc1)Oc1ccc(C(=O)Nc2cc(NC(=O)c3ccc(OC(=O)Oc4ccccc4)cc3)nc(NC(=O)c3ccc(OC(=O)Oc4ccccc4)cc3)n2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 5/20 0.50
GRM5 P41594 1/20 0.50
MEN1 O00255 5/20 0.48
KMT2A Q03164 5/20 0.48
KDM4E B2RXH2 1/20 0.48
MAPT P10636 1/20 0.48
RECQL P46063 1/20 0.48
ADORA1 P30542 3/20 0.48
NPC1 O15118 3/20 0.46
RAB9A P51151 3/20 0.46
CASP3 P42574 1/20 0.46
SENP8 Q96LD8 1/20 0.46
SENP7 Q9BQF6 1/20 0.46
SENP6 Q9GZR1 1/20 0.46
ADORA2A P29274 1/20 0.44
TP53 P04637 1/20 0.44
NFKB1 P19838 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16675203 0.89 GRM5 (0.63) ADORA3GRM5MEN1KMT2AKDM4E
SCHEMBL16675204 0.88 KMT2A (0.54) ADORA3GRM5MEN1KMT2AKDM4E
SCHEMBL16675196 0.87 MEN1 (0.56) ADORA3MEN1KMT2AKDM4EMAPT
SCHEMBL16675194 0.83 RAB9A (0.63) ADORA3MEN1KMT2AKDM4EMAPT
SCHEMBL16675189 0.80 KMT2A (0.73) ADORA3MEN1KMT2AKDM4EMAPT
SCHEMBL16675198 0.80 ELANE (0.53) ADORA3GRM5MEN1KMT2AKDM4E
SCHEMBL16675184 0.80 KMT2A (0.53) MEN1KMT2AKDM4EMAPTRECQL
SCHEMBL16675190 0.77 KMT2A (0.51) ADORA3MEN1KMT2AKDM4EMAPT
SCHEMBL16675182 0.77 KMT2A (0.63) ADORA3GRM5MEN1KMT2AKDM4E
SCHEMBL821939 0.77 ADORA1 (0.56) ADORA3GRM5MEN1KMT2AADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150114257-A1 METHOD OF PREPARING RETARDATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY Konica Minolta, Inc. (JP) 2015-04-30 US disclosed
US-20150114257-A1 METHOD OF PREPARING RETARDATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY Konica Minolta, Inc. (JP) 2015-04-30 US disclosed