SCHEMBL16675191

SCHEMBL16675191

COc1cc(C(=O)Nc2cc(NC(=O)c3cc(OC)c(OC)c(OC)c3)nc(NC(=O)c3cc(OC)c(OC)c(OC)c3)n2)cc(OC)c1OC

nearest known ligand 0.74

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 2/20 0.74
▸ USP2 O75604 1/20 0.61
▸ HSD17B10 Q99714 1/20 0.61
▸ SMN1; SMN2 Q16637 5/20 0.57
▸ MEN1 O00255 3/20 0.54
▸ KMT2A Q03164 3/20 0.54
▸ LMNA P02545 2/20 0.54
▸ MAPK1 P28482 2/20 0.54
▸ PKM P14618 1/20 0.54
▸ ABCB1 P08183 2/20 0.54
▸ BRD4 O60885 2/20 0.53
▸ MAPT P10636 2/20 0.53
▸ RAB9A P51151 1/20 0.53
▸ ABCC1 P33527 1/20 0.52
▸ ALDH1A1 P00352 1/20 0.51
▸ GFER P55789 1/20 0.51
▸ MCL1 Q07820 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15308165 0.94 POLB (0.67) POLBUSP2HSD17B10SMN1; SMN2MEN1
SCHEMBL16675210 0.92 POLB (0.64) POLBUSP2HSD17B10SMN1; SMN2MEN1
SCHEMBL18891422 0.84 POLB (0.54) POLBUSP2HSD17B10SMN1; SMN2MEN1
SCHEMBL821702 0.83 POLB (0.53) POLBUSP2HSD17B10SMN1; SMN2MEN1
SCHEMBL16675200 0.79 TOP1 (0.62) POLBUSP2HSD17B10SMN1; SMN2MEN1
SCHEMBL15308164 0.79 KMT2A (0.65) POLBSMN1; SMN2MEN1KMT2ALMNA
SCHEMBL16675189 0.77 KMT2A (0.73) SMN1; SMN2MEN1KMT2APKMMAPT
SCHEMBL16803275 0.76 MEN1 (0.55) POLBUSP2HSD17B10SMN1; SMN2MEN1
SCHEMBL11401560 0.75 L3MBTL1 (0.82) HSD17B10SMN1; SMN2MEN1KMT2ALMNA
SCHEMBL16675185 0.75 RXFP1 (0.71) POLBHSD17B10SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150114257-A1 METHOD OF PREPARING RETARDATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY Konica Minolta, Inc. (JP) 2015-04-30 — — US disclosed
US-20150114257-A1 METHOD OF PREPARING RETARDATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY Konica Minolta, Inc. (JP) 2015-04-30 — — US disclosed
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