Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4320788 | 0.87 | KMT2A (0.69) | MEN1KMT2ALMNAMAPK1PKM | |
| SCHEMBL5983029 | 0.80 | ADORA3 (0.55) | MEN1KMT2ALMNASMN1; SMN2MAPT | |
| SCHEMBL8992750 | 0.78 | POLB (0.53) | MEN1KMT2ALMNAMAPK1PKM | |
| SCHEMBL16675191 | 0.76 | POLB (0.74) | MEN1KMT2ALMNAMAPK1PKM | |
| SCHEMBL16756985 | 0.75 | RAB9A (0.55) | PKMPOLBSMN1; SMN2RXFP1ALDH1A1 | |
| SCHEMBL16248327 | 0.74 | TUBB4A (0.65) | MEN1KMT2ALMNAMAPK1POLB | |
| SCHEMBL210467 | 0.74 | KMT2A (0.64) | MEN1KMT2ALMNAMAPTRXFP1 | |
| SCHEMBL10686355 | 0.73 | ABCB1 (0.53) | MEN1KMT2ALMNAMAPK1PKM | |
| SCHEMBL11401560 | 0.73 | L3MBTL1 (0.82) | MEN1KMT2ALMNAMAPK1PKM | |
| SCHEMBL20494920 | 0.73 | GRM5 (0.66) | MEN1KMT2APOLBL3MBTL1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160312261-A1 | ENZYMATIC PRODUCTION OF CYTOSINIC NUCLEOSIDE ANALOGUES | PLASMIA BIOTECH, S.L. (ES) | 2016-10-27 | — | — | US | disclosed |
| US-20160312261-A1 | ENZYMATIC PRODUCTION OF CYTOSINIC NUCLEOSIDE ANALOGUES | PLASMIA BIOTECH, S.L. (ES) | 2016-10-27 | — | — | US | disclosed |
| EP-2883959-A1 | Enzymatic production of cytosinic nucleoside analogues | Plasmia Biotech, S.L. (ES) | 2015-06-17 | — | — | EP | disclosed |