SCHEMBL16675199

SCHEMBL16675199

CCCCC(CC)C(=O)Oc1ccc(C(=O)Nc2cc(NC(=O)c3ccc(OC(=O)C(CC)CCCC)cc3)nc(NC(=O)c3ccc(OC(=O)C(CC)CCCC)cc3)n2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.49
XBP1 P17861 1/20 0.49
ATM Q13315 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
NPC1 O15118 5/20 0.47
RAB9A P51151 5/20 0.47
MAPT P10636 4/20 0.47
SMN1; SMN2 Q16637 4/20 0.47
TP53 P04637 4/20 0.47
LMNA P02545 3/20 0.47
HSD17B10 Q99714 1/20 0.47
KMT2A Q03164 2/20 0.44
CHRNB2 P17787 7/20 0.43
CHRNA4 P43681 7/20 0.43
CHRNB4 P30926 6/20 0.43
CHRNA3 P32297 6/20 0.43
STK25 O00506 1/20 0.43
KDM4E B2RXH2 1/20 0.42
MEN1 O00255 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16675198 0.80 ELANE (0.53) NPSR1NPC1RAB9AMAPTSMN1; SMN2
SCHEMBL16675184 0.78 KMT2A (0.53) GAANPSR1NPC1RAB9AMAPT
SCHEMBL16675196 0.77 MEN1 (0.56) GAANPSR1L3MBTL1NPC1RAB9A
SCHEMBL16675194 0.76 RAB9A (0.63) NPSR1NPC1RAB9AMAPTSMN1; SMN2
SCHEMBL16675190 0.73 KMT2A (0.51) L3MBTL1NPC1RAB9AMAPTSMN1; SMN2
SCHEMBL16675189 0.73 KMT2A (0.73) GAAL3MBTL1NPC1RAB9AMAPT
SCHEMBL26985478 0.73 L3MBTL1 (0.61) GAAXBP1ATMNPSR1L3MBTL1
SCHEMBL27314199 0.73 L3MBTL1 (0.65) GAAXBP1ATMNPSR1L3MBTL1
SCHEMBL13030461 0.72 GAA (0.65) GAAXBP1ATMNPSR1L3MBTL1
SCHEMBL2294906 0.71 L3MBTL1 (0.59) GAAXBP1ATMNPSR1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150114257-A1 METHOD OF PREPARING RETARDATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY Konica Minolta, Inc. (JP) 2015-04-30 US disclosed
US-20150114257-A1 METHOD OF PREPARING RETARDATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY Konica Minolta, Inc. (JP) 2015-04-30 US disclosed