SCHEMBL16675208

SCHEMBL16675208

O=C(Nc1cc(NC(=O)c2ccc(OC(=O)C3CCCCC3)cc2)nc(NC(=O)c2ccc(OC(=O)C3CCCCC3)cc2)n1)c1ccc(OC(=O)C2CCCCC2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.52
ELANE P08246 2/20 0.52
KMT2A Q03164 6/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
HTT P42858 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
MEN1 O00255 3/20 0.47
MAPT P10636 3/20 0.47
L3MBTL1 Q9Y468 1/20 0.45
KDM4E B2RXH2 2/20 0.44
ALDH1A1 P00352 2/20 0.44
GLA P06280 1/20 0.44
GAA P10253 1/20 0.44
CA2 P00918 1/20 0.44
ADORA3 P0DMS8 2/20 0.43
RECQL P46063 1/20 0.43
NPC1 O15118 3/20 0.43
RAB9A P51151 3/20 0.43
LMNA P02545 2/20 0.43
USP2 O75604 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16675206 0.88 MAPT (0.44) POLBELANEKMT2ASMN1; SMN2HTT
SCHEMBL16675194 0.78 RAB9A (0.63) POLBELANEKMT2ASMN1; SMN2HTT
SCHEMBL16677988 0.78 POLB (0.54) POLBELANEKMT2ASMN1; SMN2HTT
SCHEMBL16677951 0.78 POLB (0.54) POLBELANEKMT2ASMN1; SMN2HTT
SCHEMBL16677970 0.77 KMT2A (0.58) POLBELANEKMT2ASMN1; SMN2HTT
SCHEMBL16675196 0.77 MEN1 (0.56) KMT2ASMN1; SMN2MEN1MAPTL3MBTL1
SCHEMBL16675192 0.76 ADORA3 (0.50) KMT2ASMN1; SMN2MEN1MAPTKDM4E
SCHEMBL10574401 0.75 KMT2A (0.88) POLBELANEKMT2ASMN1; SMN2HTT
SCHEMBL16675189 0.74 KMT2A (0.73) KMT2ASMN1; SMN2MEN1MAPTL3MBTL1
SCHEMBL16675198 0.74 ELANE (0.53) POLBELANEKMT2ASMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150114257-A1 METHOD OF PREPARING RETARDATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY Konica Minolta, Inc. (JP) 2015-04-30 US disclosed
US-20150114257-A1 METHOD OF PREPARING RETARDATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY Konica Minolta, Inc. (JP) 2015-04-30 US disclosed