Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.45 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28303907 | 0.88 | ALDH1A1 (0.51) | ALDH1A1CYP3A4TSHRCYP2C19HIF1A | |
| SCHEMBL7695920 | 0.85 | ALDH1A1 (0.51) | ALDH1A1CYP3A4TSHRCYP2C19HIF1A | |
| SCHEMBL3825965 | 0.85 | CYP1A2 (0.58) | ALDH1A1CYP3A4TSHRCYP2C19LMNA | |
| SCHEMBL11989937 | 0.80 | OPRM1 (0.58) | ALDH1A1CYP3A4TSHRCYP2C19LMNA | |
| SCHEMBL23682540 | 0.79 | OPRM1 (0.59) | ALDH1A1CYP3A4TSHRCYP2C19LMNA | |
| SCHEMBL12508381 | 0.78 | KCNA5 (0.48) | ALDH1A1CYP3A4TSHRCYP2C19HIF1A | |
| SCHEMBL1303683 | 0.77 | DPP4 (0.53) | ALDH1A1CYP3A4TSHRCYP2C19LMNA | |
| SCHEMBL11651599 | 0.77 | OPRL1 (0.58) | ALDH1A1CYP3A4TSHRCYP2C19HIF1A | |
| SCHEMBL1711539 | 0.77 | OPRM1 (0.56) | ALDH1A1CYP3A4TSHRCYP2C19HIF1A | |
| SCHEMBL11990089 | 0.77 | KCNA5 (0.47) | ALDH1A1CYP3A4TSHRCYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2482815-A1 | ANTI INFLAMMATORY 2-OXOTHIAZOLES AND 2 -OXOOXAZOLES | Avexxin AS (NO) | 2012-08-08 | — | — | EP | disclosed |
| WO-2011039365-A1 | ANTI INFLAMMATORY 2-OXOTHIAZOLES AND 2 -OXOOXAZOLES | AVEXXIN AS (NO) | 2011-04-07 | — | — | WO | disclosed |